一名儿科患者因烧伤导致心肌抑制，进而引发暴发性心源性休克和多器官功能衰竭，需要体外生命支持。
Burn-induced myocardial depression in a pediatric patient leading to fulminant cardiogenic shock and multiorgan failure requiring extracorporeal life support.
作者信息
Panchal Apurva, Casadonte Joseph
机构信息
Department of Pediatrics University of Kansas Health System Kansas City KS USA.
Department of Pediatrics Dell Children's Medical Center of Central Texas Austin TX USA.
出版信息
Clin Case Rep. 2020 Feb 22;8(4):602-605. doi: 10.1002/ccr3.2667. eCollection 2020 Apr.
Abstract
Cardiac stress is a critical determinant of outcomes associated with severe thermal injury. The cardiovascular response to a catecholamine-mediated surge from severe burns passes through two phases. Initial hypovolemia with myocardial depression leads to a low cardiac output, which then progresses to a hyperdynamic-hypermetabolic phase with increased cardiac output.
摘要
心脏应激是严重热损伤相关预后的关键决定因素。严重烧伤引起的儿茶酚胺介导的激增所引发的心血管反应经历两个阶段。最初的低血容量伴心肌抑制导致心输出量降低，随后发展为心输出量增加的高动力-高代谢阶段。
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本文引用的文献
1
Inflammation and cardiac dysfunction during sepsis, muscular dystrophy, and myocarditis.脓毒症、肌肉萎缩症和心肌炎时的炎症和心功能障碍。
Burns Trauma. 2013 Dec 18;1(3):109-21. doi: 10.4103/2321-3868.123072. eCollection 2013.
2
Cardiovascular dysfunction in burns: review of the literature.烧伤中的心血管功能障碍：文献综述
Ann Burns Fire Disasters. 2012 Mar 31;25(1):26-37.
3
Changes in cardiac physiology after severe burn injury.严重烧伤后心脏生理功能的变化。
J Burn Care Res. 2011 Mar-Apr;32(2):269-74. doi: 10.1097/BCR.0b013e31820aafcf.
4
The hypermetabolic response to burn injury and interventions to modify this response.烧伤后的高代谢反应以及改变这种反应的干预措施。
Clin Plast Surg. 2009 Oct;36(4):583-96. doi: 10.1016/j.cps.2009.05.001.
5
Decreased fluid volume to reduce organ damage: a new approach to burn shock resuscitation? A preliminary study.减少液体量以减轻器官损伤：烧伤休克复苏的新方法？一项初步研究。
Resuscitation. 2007 Mar;72(3):371-8. doi: 10.1016/j.resuscitation.2006.07.010. Epub 2006 Nov 29.
6
Myocardial function following thermal injury.热损伤后的心肌功能
Circ Res. 1962 Oct;11:669-73. doi: 10.1161/01.res.11.4.669.
7
The risk factors and time course of sepsis and organ dysfunction after burn trauma.烧伤创伤后脓毒症和器官功能障碍的危险因素及时间进程。
J Trauma. 2003 May;54(5):959-66. doi: 10.1097/01.TA.0000029382.26295.AB.
8
Fatal catecholamine myocarditis in a child with severe scalding injury.一名重度烫伤儿童发生致命性儿茶酚胺性心肌炎。
Intensive Care Med. 2002 Nov;28(11):1687-8. doi: 10.1007/s00134-002-1493-1.
9
Effect of propranolol administration on hemodynamic and metabolic responses of burned pediatric patients.普萘洛尔给药对烧伤小儿患者血流动力学和代谢反应的影响。
Ann Surg. 1988 Oct;208(4):484-92. doi: 10.1097/00000658-198810000-00010.
10
Effects of beta adrenergic blocking agents upon thermal trauma induced cardiovascular changes.
Arch Int Pharmacodyn Ther. 1979 Apr;238(2):296-304.
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