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多灶性遗传性骨软骨瘤病伴多轴向肢体畸形患者行全膝关节置换术联合胫骨干骺端截骨术:1 例报告

Total knee arthroplasty with simultaneous tibial shaft osteotomy in patient with multiple hereditary osteochondromas and multiaxial limb deformity - a case report.

机构信息

Department of Orthopaedics and Rheumoortopaedics, Professor Adam Gruca Teaching Hospital, Centre of Postgraduate Medical Education, Konarskiego 13, 05-400, Otwock, Poland.

Department of Traumatology and Orthopaedic Surgery, Professor Adam Gruca Teaching Hospital, Centre of Postgraduate Medical Education, Konarskiego 13, 05-400, Otwock, Poland.

出版信息

BMC Musculoskelet Disord. 2020 Apr 13;21(1):233. doi: 10.1186/s12891-020-03245-x.

DOI:10.1186/s12891-020-03245-x
PMID:32284061
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7155326/
Abstract

BACKGROUND

Hereditary multiple osteochondromas (hereditary multiple exostoses, HME) is a rare genetic disease characterized by the development of benign osteocartilaginous tumors that may cause severe limb deformities and early onset osteoarthritis. Total knee arthroplasty (TKA) is the method of choice for the treatment of advanced gonarthrosis, however the surgical management with coexisting severe axial limb deformity remains unclear.

CASE PRESENTATION

65-year-old man with HME and extra-articular multi-axial limb deformity was admitted to the orthopedic department due to chronic knee pain and limited range of motion caused by secondary osteoarthritis. Regarding to the clinical and radiological examinations, after preoperative planning he was qualified to a one-stage TKA combined with tibial shaft osteotomy (TSO). In a one year follow-up full bone union was confirmed with no signs of implant loosening or prosthesis displacement. Patient was very satisfied, did not report any joint pain and has sufficient range of motion without knee instability.

CONCLUSION

The improvement of mechanical axis during TKA is a crucial factor for achieve operative success and long implant survival. Despite the higher risk of complication rate in comparison to two-stage treatment, one-stage TKA with simultaneous TSO should be a considerable method for patients with osteoarthritis and multiaxial limb deformities. This method can give a good clinical and functional outcomes, however should be performed subsequently to careful preoperative planning and proper patient qualification.

摘要

背景

遗传性多发性骨软骨瘤(遗传性多发性外生骨疣,HME)是一种罕见的遗传病,其特征是良性骨软骨肿瘤的发展,可能导致严重的肢体畸形和早期骨关节炎。全膝关节置换术(TKA)是治疗晚期膝关节骨关节炎的首选方法,然而对于同时存在严重轴向肢体畸形的患者,手术管理仍不清楚。

病例介绍

一名 65 岁男性,患有 HME 和关节外多轴向肢体畸形,因继发性骨关节炎引起的慢性膝关节疼痛和活动范围受限而入住骨科。根据临床和影像学检查,经过术前规划,他符合一期 TKA 联合胫骨骨干截骨术(TSO)的条件。在一年的随访中,完全骨愈合得到了确认,没有出现植入物松动或假体移位的迹象。患者非常满意,没有报告任何关节疼痛,并且具有足够的活动范围,没有膝关节不稳定。

结论

TKA 过程中机械轴的改善是手术成功和长期植入物存活的关键因素。尽管与两阶段治疗相比,并发症发生率的风险更高,但对于患有骨关节炎和多轴向肢体畸形的患者,一期 TKA 联合 TSO 应是一种可行的方法。该方法可获得良好的临床和功能结果,但应在仔细的术前规划和适当的患者资格评估后进行。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b35/7155326/f837768aebc2/12891_2020_3245_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b35/7155326/c45e8e6f091e/12891_2020_3245_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b35/7155326/02b55876a57b/12891_2020_3245_Fig2_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b35/7155326/228f0998ab70/12891_2020_3245_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b35/7155326/f837768aebc2/12891_2020_3245_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b35/7155326/c45e8e6f091e/12891_2020_3245_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b35/7155326/02b55876a57b/12891_2020_3245_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b35/7155326/1900298d8080/12891_2020_3245_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b35/7155326/228f0998ab70/12891_2020_3245_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b35/7155326/f837768aebc2/12891_2020_3245_Fig5_HTML.jpg

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