Research in Orthopedic Computer Science, Balgrist University Hospital, CH-8008, Zurich, Switzerland.
Laboratory for Orthopaedic Biomechanics, Institute for Biomechanics, ETH Zurich, CH-8008, Zurich, Switzerland.
Sci Rep. 2020 Apr 14;10(1):6401. doi: 10.1038/s41598-020-63436-3.
State-of-the-art of preoperative planning for forearm orthopaedic surgeries is currently limited to simple bone procedures. The increasing interest of clinicians for more comprehensive analysis of complex pathologies often requires dynamic models, able to include the soft tissue influence into the preoperative process. Previous studies have shown that the interosseous membrane (IOM) influences forearm motion and stability, but due to the lack of morphological and biomechanical data, existing simulation models of the IOM are either too simple or clinically unreliable. This work aims to address this problematic by generating 3D morphological and tensile properties of the individual IOM structures. First, micro- and standard-CT acquisitions were performed on five fresh-frozen annotated cadaveric forearms for the generation of 3D models of the radius, ulna and each of the individual ligaments of the IOM. Afterwards, novel 3D methods were developed for the measurement of common morphological features, which were validated against established optical ex-vivo measurements. Finally, we investigated the individual tensile properties of each IOM ligament. The generated 3D morphological features can provide the basis for the future development of functional planning simulation of the forearm.
目前，前臂骨科手术的术前规划处于先进水平，但仅限于简单的骨骼手术。临床医生对更全面的复杂病理分析越来越感兴趣，这通常需要能够将软组织影响纳入术前过程的动态模型。先前的研究表明，骨间膜（IOM）会影响前臂的运动和稳定性，但由于缺乏形态学和生物力学数据，现有的 IOM 模拟模型要么过于简单，要么在临床上不可靠。这项工作旨在通过生成个体 IOM 结构的 3D 形态和拉伸特性来解决这个问题。首先，对五个新鲜冷冻的解剖前臂进行微 CT 和标准 CT 采集，以生成桡骨、尺骨和 IOM 各个单独韧带的 3D 模型。然后，开发了新的 3D 方法来测量常见的形态特征，并通过已建立的离体光学测量进行验证。最后，我们研究了每个 IOM 韧带的个体拉伸特性。生成的 3D 形态特征可为未来前臂功能规划模拟的发展提供基础。
