Swine Research Center, School of Veterinary Medicine and Animal Science, University of São Paulo, Av. Duque de Caxias Norte, 225, Pirassununga13635-900, Brazil.
Faculty of Animal Science and Food Engineering, University of São Paulo, Av. Duque de Caxias Norte, 225, Pirassununga13635-900, Brazil.
Animal. 2020 Sep;14(9):1899-1905. doi: 10.1017/S1751731120000658. Epub 2020 Apr 15.
The use of altrenogest (ALT) supplementation for oestrous synchronization improves subsequent reproductive performance of gilts and sows. However, the causes of this improvement in reproductive performance after ALT treatment are not fully/clearly understood. The objective of this study was to evaluate the effects of ALT supplementation for oestrous synchronization in gilts on the endometrial glands and embryonic development characteristics at 28 days of pregnancy. Pregnant gilts were divided into two experimental treatments: Control (did not receive ALT; n = 9 gilts) and ALT (ALT feeding at 20 mg/day for 18 days; n = 9 gilts). At 28 days of pregnancy, six gilts from each treatment were slaughtered, and reproductive tracts were immediately evaluated. There was no statistical difference (P > 0.05) between treatments regarding ovulation rate, number of embryos, number of vital embryos and number of non-vital embryos. Embryo weight, length and embryonic vesicle weight were lower in ALT treatment compared with Control (P < 0.01), and it was lower in the cervical uterine region compared with apex uterine region, respectively (P < 0.05). Higher values of gland duct area, gland duct perimeter, percentage of the glandular area and total endometrial area were observed in ALT treatment compared with Control (P < 0.05). The use of ALT during 18 days for oestrous synchronization in gilts increased the gland duct area, perimeter and total endometrial area but did not increase the embryo number and embryo size at day 28 of pregnancy.
使用阿尔腾诺杰斯特（ALT）补充剂进行发情同步可提高后备母猪和经产母猪的后续繁殖性能。然而，在 ALT 处理后繁殖性能提高的原因尚不完全/清楚。本研究的目的是评估 ALT 补充剂对发情同步后备母猪的子宫内膜腺和妊娠 28 天胚胎发育特征的影响。妊娠母猪分为两个实验组：对照组（未接受 ALT；n = 9 头母猪）和 ALT 组（每天 ALT 喂养 20mg，共 18 天；n = 9 头母猪）。在妊娠 28 天时，每组从 6 头母猪中随机屠宰，并立即评估生殖道。排卵率、胚胎数、活胚胎数和死胚胎数在两组间无统计学差异（P>0.05）。与对照组相比，ALT 处理组胚胎重量、长度和胚胎泡重量较低（P<0.01），且在宫颈区较低，而在子宫角区较高（P<0.05）。与对照组相比，ALT 处理组的腺管面积、腺管周长、腺腔面积百分比和总子宫内膜面积较高（P<0.05）。在发情同步期间，18 天内使用 ALT 增加了后备母猪的腺管面积、周长和总子宫内膜面积，但在妊娠第 28 天没有增加胚胎数量和胚胎大小。
