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肥胖状态是创伤性臂丛神经损伤行神经松解术、直接神经修复术或神经移植术后二次手术的危险因素:一项回顾性队列研究。

Obesity status is a risk factor for secondary surgery after neurolysis, direct nerve repair or nerve grafting in traumatic brachial plexus injury: a retrospective cohort study.

作者信息

Atthakomol Pichitchai, Oflazoglu Kamilcan, Eberlin Kyle R, Winograd Jonathan, Chen Neal C, Lee Sang-Gil

机构信息

Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA, USA.

Department of Orthopaedics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

出版信息

BMC Surg. 2020 Apr 15;20(1):73. doi: 10.1186/s12893-020-00737-4.

Abstract

BACKGROUND

The objective of the study was to investigate the association between obesity and the presence of secondary surgery following neurolysis, direct nerve repair, or nerve grafting in patients with traumatic brachial plexus injury.

METHODS

In this retrospective chart review spanning two Level I medical centers in a single metropolitan area, 57 patients who underwent neurolysis, direct nerve repair, or nerve grafting for brachial plexus injuries between 2002 and 2015 were identified. Risk regression analysis was used to evaluate the association between obesity status and secondary surgery.

RESULTS

After controlling for the confounding variables of age, high energy injury, associated shoulder dislocation and associated clavicle fracture using multivariate regression (risk regression), the risk ratio of secondary surgery in obese patients compared to non-obese patients was 6.99 (P = 0.028). The most common secondary surgery was tendon or local muscle transfer.

CONCLUSIONS

There is an increased risk of secondary surgery in obese patients compared to non-obese patients of the same age and with the same severity of injury. The increased risk may be due to challenges related to powering a heavier upper extremity. A weight reduction program might be considered as part of the preoperative strategy.

摘要

背景

本研究的目的是调查肥胖与创伤性臂丛神经损伤患者在神经松解、直接神经修复或神经移植术后二次手术之间的关联。

方法

在对一个大都市地区两个一级医疗中心进行的这项回顾性病历审查中,确定了2002年至2015年间因臂丛神经损伤接受神经松解、直接神经修复或神经移植的57例患者。采用风险回归分析评估肥胖状态与二次手术之间的关联。

结果

在使用多因素回归(风险回归)控制年龄、高能量损伤、相关肩关节脱位和相关锁骨骨折等混杂变量后,肥胖患者与非肥胖患者相比二次手术的风险比为6.99(P = 0.028)。最常见的二次手术是肌腱或局部肌肉转移。

结论

与年龄相同且损伤严重程度相同的非肥胖患者相比,肥胖患者二次手术的风险增加。风险增加可能是由于驱动较重的上肢存在困难。减重计划可作为术前策略的一部分予以考虑。

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