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一项关于脊柱手术中意外硬脊膜撕裂处理的系统评价和荟萃分析:信息泛滥却渴望明确的信息。

A systematic review and meta-analysis on the management of accidental dural tears in spinal surgery: drowning in information but thirsty for a clear message.

作者信息

Alshameeri Zeiad A F, El-Mubarak Ahmed, Kim Edward, Jasani Vinay

机构信息

Spinal Surgery Department, Royal Stoke University Hospital, Newcastle Rd, Stoke-on-Trent, ST4 6QG, UK.

出版信息

Eur Spine J. 2020 Jul;29(7):1671-1685. doi: 10.1007/s00586-020-06401-y. Epub 2020 Apr 15.

Abstract

PURPOSE

To systematically review the published techniques for dural tear (DT) repair in spinal surgery to determine the repair method associated with the lowest failure rate.

METHOD

A systematic literature search was conducted. Studies reporting the treatment of accidental DT in elective spinal surgery were selected and reviewed with regards to the incidence of DT, repair techniques and outcome. Meta-analysis of proportions was used to compare the outcome of different repair techniques and their adjuncts.

RESULTS

Forty-nine studies were included with a total of 3822 DT cases. The outcome of different dural repair techniques was available for 2329(60.9%) cases. The overall pooled risk of DT was 0.052(0.040-0.065) and the overall pooled proportion of failed DT treatment regardless of the treatment method was 0.061(0.044-0.083). The proportion of failure varied according to the repair method. The overall proportion of failure following direct repair with suture (with or without any other augment) was lower than indirect repair (with sealant and or patch): 0.037 (0.024-0.053) versus 0.047 (0.026-0.074), respectively. Bed rest and the use of sub-fascial drain were not associated with improved outcome according to our results.

CONCLUSION

Direct repair was associated with low proportion of failure. Howver, the approach to DT treatment was commonly determined on an ad hoc basis according to surgeons' preferences, and few followed defined management protocols. Future studies reporting DT treatment ought to categorise the treatment outcome according to the complexity of the DT and the specific treatment used, thus improving research quality in the field.

摘要

目的

系统回顾脊柱手术中硬脑膜撕裂(DT)修复的已发表技术,以确定失败率最低的修复方法。

方法

进行系统的文献检索。选择报告择期脊柱手术中意外DT治疗的研究,并就DT的发生率、修复技术和结果进行综述。采用比例的荟萃分析来比较不同修复技术及其辅助手段的结果。

结果

纳入49项研究,共3822例DT病例。2329例(60.9%)病例有不同硬脑膜修复技术的结果。DT的总体合并风险为0.052(0.040 - 0.065),无论治疗方法如何DT治疗失败的总体合并比例为0.061(0.044 - 0.083)。失败比例因修复方法而异。直接缝合修复(无论有无其他增强措施)后的总体失败比例低于间接修复(使用密封剂和/或补片):分别为0.037(0.024 - 0.053)和0.

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