Gubatan John, Shah Nimeesh
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA.
Division of Gastroenterology and Hepatology, Santa Clara Valley Medical Center, San Jose, CA.
ACG Case Rep J. 2020 Jan 7;7(1):e00301. doi: 10.14309/crj.0000000000000301. eCollection 2020 Jan.
Gastrointestinal bleeding from percutaneous endoscopic gastrostomy tubes and malignancy are uncommon. Gastric leiomyosarcomas are rare and differentiated from other gastric tumors with histology and immunohistochemical staining. We present a case of upper gastrointestinal bleeding from a percutaneous endoscopic gastrostomy tube manifesting as a gastric leiomyosarcoma in a 50-year-old man with a medical history of Wilms tumor. We reviewed the epidemiology, diagnosis, and management of gastric leiomyosarcomas. We also explored the risk factors and potential mechanisms in the pathogenesis of gastric leiomyosarcoma in our patient.
经皮内镜下胃造瘘管及恶性肿瘤引起的胃肠道出血并不常见。胃平滑肌肉瘤罕见,可通过组织学和免疫组化染色与其他胃肿瘤相鉴别。我们报告一例50岁有肾母细胞瘤病史男性患者,经皮内镜下胃造瘘管引起上消化道出血,病理显示为胃平滑肌肉瘤。我们回顾了胃平滑肌肉瘤的流行病学、诊断及治疗方法。我们还探究了该患者胃平滑肌肉瘤发病机制中的危险因素及潜在机制。