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内镜超声和内镜逆行胰胆管造影在儿童慢性胰腺炎的评估和治疗中的作用:北美儿童胃肠病学、肝病学和营养学协会胰腺委员会的立场文件。

The Roles of Endoscopic Ultrasound and Endoscopic Retrograde Cholangiopancreatography in the Evaluation and Treatment of Chronic Pancreatitis in Children: A Position Paper From the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Pancreas Committee.

机构信息

Cedars-Sinai Medical Center, David Geffen School of Medicine at UCLA, Los Angeles.

Lucile Packard Children's Hospital at Stanford and the Department of Pediatrics, Stanford University, Palo Alto, CA.

出版信息

J Pediatr Gastroenterol Nutr. 2020 May;70(5):681-693. doi: 10.1097/MPG.0000000000002664.

Abstract

INTRODUCTION

Pediatric chronic pancreatitis is increasingly diagnosed. Endoscopic methods [endoscopic ultrasound (EUS), endoscopic retrograde cholangiopancreatography (ERCP)] are useful tools to diagnose and manage chronic pancreatitis. Pediatric knowledge and use of these modalities is limited and warrants dissemination.

METHODS

Literature review of publications relating to use of ERCP and EUS for diagnosis and/or management of chronic pancreatitis with special attention to studies involving 0--18 years old subjects was conducted with summaries generated. Recommendations were developed and voted upon by authors.

RESULTS

Both EUS and ERCP can be used even in small children to assist in diagnosis of chronic pancreatitis in cases where cross-sectional imaging is not sufficient to diagnose or characterize the disease. Children under 15 kg for EUS and 10 kg for ERCP can be technically challenging. These procedures should be done optimally by appropriately trained endoscopists and adult gastroenterology providers with appropriate experience treating children. EUS and ERCP-related risks both include perforation, bleeding and pancreatitis. EUS is the preferred diagnostic modality over ERCP because of lower complication rates overall. Both modalities can be used for management of chronic pancreatitis -related fluid collections. ERCP has successfully been used to manage pancreatic duct stones.

CONCLUSION

EUS and ERCP can be safely used to diagnose chronic pancreatitis in pediatric patients and assist in management of chronic pancreatitis-related complications. Procedure-related risks are similar to those seen in adults, with EUS having a safer risk profile overall. The recent increase in pediatric-trained specialists will improve access of these modalities for children.

摘要

简介

小儿慢性胰腺炎的诊断率逐渐升高。内镜方法(内镜超声检查(EUS)、内镜逆行胰胆管造影术(ERCP))是诊断和治疗慢性胰腺炎的有用工具。儿科医生对这些方法的了解和应用有限,因此需要进行传播。

方法

对涉及 ERCP 和 EUS 用于诊断和/或管理慢性胰腺炎的文献进行了回顾,特别关注了涉及 0-18 岁患者的研究,并进行了总结。建议由作者制定并投票。

结果

EUS 和 ERCP 均可用于诊断慢性胰腺炎,即使在不能通过横断面成像充分诊断或确定疾病特征的情况下也可使用。对于 EUS,体重小于 15kg 的儿童和 ERCP,体重小于 10kg 的儿童可能在技术上具有挑战性。这些程序应由经过适当培训的内镜医生和具有适当治疗儿童经验的成人胃肠病学提供者来最佳完成。EUS 和 ERCP 相关的风险均包括穿孔、出血和胰腺炎。由于总体并发症发生率较低,EUS 是优于 ERCP 的首选诊断方法。两种方法均可用于管理慢性胰腺炎相关的液体积聚。ERCP 已成功用于治疗胰管结石。

结论

EUS 和 ERCP 可安全用于诊断小儿慢性胰腺炎,并有助于治疗慢性胰腺炎相关并发症。与成人相比,这些方法的相关风险相似,总体而言 EUS 的风险状况更安全。最近增加了儿科专业人员,将改善儿童获得这些方法的机会。

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