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下颌骨骨坏死与双膦酸盐有关:一例极为罕见的广泛病例。

Osteonecrosis Mandibular Extended to Bisphosphonates: A Very Rare Extensive Case.

作者信息

Khalfi Lahcen, Ndiaye Abibou, Chabi Wilfried, Fiqhi Mohammed Kamal, El Khatib Karim

机构信息

Plastic and Maxillo-Facial Surgery, Mohammed V Teaching Armed Forces Hospital, Rabat, MAR.

Surgery, Mohammed V Teaching Armed Forces Hospital, Rabat, MAR.

出版信息

Cureus. 2020 Mar 26;12(3):e7428. doi: 10.7759/cureus.7428.

Abstract

After the first report of bisphosphonate-related osteonecrosis of the jaw (BRONJ) in 2003, it has increased significantly since then. We report a very rare extensive case never seen before in our experience of bone exposure with necrosis reaching the mandibular inferior border. Although the treatment modalities are not yet established, most researchers have recommended conservative approaches. The surgery was to be as conservative as possible, with a resection of the mandibular range followed by reconstruction using titanium plate with space maintainer. The authors would like to share their approach, management, and awareness.

摘要

自2003年首次报告双膦酸盐相关颌骨坏死(BRONJ)以来,其发病率此后显著上升。我们报告了一例极为罕见的广泛病例,在我们的经验中,从未见过骨暴露坏死至下颌下缘的情况。尽管治疗方式尚未确立,但大多数研究人员推荐采用保守方法。手术应尽可能保守,切除下颌骨范围后,使用带间隙保持器的钛板进行重建。作者希望分享他们的治疗方法、管理经验及认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a00f/7186105/e670851a655a/cureus-0012-00000007428-i01.jpg

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