Rahman Khaliqur, Harankhedkar Shivangi, Gupta Ruchi, Gupta Tanvi, Sharma Seema, Nityanand Soniya
Department of Hematology, SGPGI, Lucknow, Uttar Pradesh, India.
Department of Pathology, SGPGI, Lucknow, Uttar Pradesh, India.
J Cancer Res Ther. 2020 Jan-Mar;16(1):164-166. doi: 10.4103/jcrt.JCRT_1413_16.
Filariasis is among the common parasitic infestations found in India, with Wuchereria bancrofti being the most common causative organism. Presentation ranges from clinically asymptomatic to profound elephantiasis. It is also detected incidentally in diagnostic samples such as body fluids, fine needle aspirates, peripheral blood smears, and other cytological smears. Its detection in bone marrow aspirates with an associated hematolymphoid neoplasm is rare, with only a few case reports. We report one such case of young male who presented with leukocytosis of 253 × 10/L with basophilia and massive splenomegaly. Bone marrow aspirate smears showed the presence of microfilariae along with other features of a myeloproliferative neoplasm (MPN). The present case is probably the first case of finding a microfilaria in a case of MPN.
丝虫病是印度常见的寄生虫感染之一，班氏吴策线虫是最常见的致病生物。临床表现从临床无症状到严重象皮肿不等。在体液、细针穿刺抽吸物、外周血涂片和其他细胞学涂片等诊断样本中也可偶然检测到。在伴有血液淋巴系统肿瘤的骨髓穿刺物中检测到丝虫病很罕见，仅有少数病例报告。我们报告了这样一例年轻男性病例，其白细胞计数为253×10⁹/L，伴有嗜碱性粒细胞增多和巨大脾肿大。骨髓穿刺涂片显示存在微丝蚴以及骨髓增殖性肿瘤（MPN）的其他特征。本病例可能是首例在MPN病例中发现微丝蚴的病例。
