随访期间细胞学恶化和病变增大是宫颈管小叶状腺增生恶变的有用指标：一例报告
Worsening cytology and lesion enlargement are useful indicators for malignant transformation of lobular endocervical glandular hyperplasia during follow-up: A case report.
作者信息
Kobara Hisanori, Miyamoto Tsutomu, Otsuki Toshiaki, Ohya Ayumi, Shiozawa Tanri
机构信息
Department of Obstetrics and Gynecology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan.
Department of Laboratory Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan.
出版信息
Gynecol Oncol Rep. 2020 Apr 11;32:100571. doi: 10.1016/j.gore.2020.100571. eCollection 2020 May.
•We report a case of MDA arising from clinical LEGH during 5 years of follow-up.•The first sign suggesting MDA was cellular atypia in endocervical cytology, and was followed by an increase in tumor size.•MDA lesion lacked in stromal reaction and MRI failed to detected MDA.•Worsening cytology and lesion enlargement are important signs for malignant change of LEGH during follow-up.
•我们报告了1例在5年随访期间由临床诊断的LEGH发展而来的MDA病例。
•提示MDA的首个迹象是宫颈细胞学检查中的细胞异型性，随后肿瘤大小增加。
•MDA病变缺乏间质反应，MRI未能检测到MDA。
•随访期间细胞学恶化和病变增大是LEGH恶变的重要征象。
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