肥胖、多毛症与性类固醇：这些因素与藏毛窦疾病有关吗？
Obesity, Hypertrichosis and Sex Steroids: Are these Factors Related to the Pilonidal Sinus Disease?
作者信息
Ekici Uğur, Ferhatoğlu Murat Ferhat
机构信息
College of Health Sciences, Gelisim University, Istanbul, Turkey.
Department of General Surgery, Okan University Faculty of Medicine, Istanbul,Turkey.
出版信息
Sisli Etfal Hastan Tip Bul. 2019 Aug 26;53(3):263-266. doi: 10.14744/SEMB.2019.78800. eCollection 2019.
OBJECTIVES
Pilonidal sinus disease causes chronic inflammation of the skin and subcutaneous fatty tissue, and it commonly localises in the sacrococcygeal region. This study evaluated the effects of hypertrichosis, family history, obesity and sex steroids in 298 patients with pilonidal sinus disease.
METHODS
The medical records of 618 patients treated at the General Surgery Clinic of Malatya State Hospital for primary pilonidal sinus disease between January 2014 and December 2017 were evaluated retrospectively.
RESULTS
Female sex and family histories of pilonidal sinus disease and hypertrichosis were significantly higher in patients with than without hypertrichosis (p=0.030, p=0.035, p<0.001). The mean progesterone level was significantly lower in female patients with hypertrichosis than female patients without hypertrichosis (p=0.003).
CONCLUSION
Being overweight or obese, having an occupation that requires long-time sitting and having a family history predisposed to developing pilonidal sinus disease.
目的
藏毛窦疾病会导致皮肤和皮下脂肪组织的慢性炎症，且通常位于骶尾区域。本研究评估了多毛症、家族史、肥胖及性类固醇对298例藏毛窦疾病患者的影响。
方法
回顾性评估2014年1月至2017年12月在马拉蒂亚州立医院普通外科门诊接受原发性藏毛窦疾病治疗的618例患者的病历。
结果
有毛发过多的患者中，女性、藏毛窦疾病家族史和多毛症的比例显著高于无毛发过多的患者（p = 0.030，p = 0.035，p < 0.001）。有毛发过多的女性患者的平均孕酮水平显著低于无毛发过多的女性患者（p = 0.003）。
结论
超重或肥胖、从事需要长时间坐着的职业以及有家族病史易患藏毛窦疾病。
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