Masui Koji, Yamazaki Hideya, Suzuki Gen, Shimizu Daisuke, Takenaka Tadashi, Yamada Yasuhiro, Okihara Koji, Kuriu Yoshiaki, Yamada Kei
Department of Radiology, Kyoto Prefectural University Graduate School of Medical Science, Kyoto, Japan.
Department of Urology, Kyoto Prefectural University Graduate School of Medical Science, Kyoto, Japan.
J Contemp Brachytherapy. 2020 Apr;12(2):188-192. doi: 10.5114/jcb.2020.93875. Epub 2020 Mar 26.
High-dose-rate interstitial brachytherapy (HDR-ISBT) is widely used for the treatment of pelvic tumors. However, there are a few reports on complications of applicator implantation in HDR-ISBT. We describe a case of small bowel perforation caused by applicator implantation in an 82-year-old male patient with recurrence tumor in the pelvis treated with HDR-ISBT. Eventually, the patient underwent laparotomy and partial intestinal resection. We recognized the site where the applicator was inserted into a part of the tumor on the mucosal surface. Pathological examination confirmed that the tumor had infiltrated the small intestine directly and that the infiltrated part had reached the submucosa. This is the first published report about small bowel perforation caused by applicator implantation. In cases where intestinal infiltration of the tumor is suspected, HDR-ISBT should be performed with maximum caution.
高剂量率组织间近距离放射治疗(HDR-ISBT)广泛应用于盆腔肿瘤的治疗。然而,关于HDR-ISBT中施源器植入并发症的报道较少。我们描述了一例82岁男性盆腔复发性肿瘤患者,在接受HDR-ISBT治疗时因施源器植入导致小肠穿孔的病例。最终,患者接受了剖腹手术和部分肠切除术。我们发现施源器插入肿瘤黏膜表面部分的位置。病理检查证实肿瘤已直接浸润小肠,浸润部分已达黏膜下层。这是关于施源器植入导致小肠穿孔的首篇发表报道。在怀疑肿瘤侵犯肠道的病例中,应极其谨慎地进行HDR-ISBT。