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脊髓内肠源性囊肿伴胶质组织。

Intramedullary endodermal cyst including glial tissues in the spinal cord.

机构信息

Department of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan.

Division of Diagnostic Pathology, Keio University School of Medicine, Tokyo, Japan.

出版信息

Spinal Cord Ser Cases. 2020 May 13;6(1):37. doi: 10.1038/s41394-020-0287-4.

Abstract

INTRODUCTION

Spinal intramedullary endodermal cyst is a rare spinal cord tumour. In particular, an endodermal cyst that includes glial tissues is extremely rare. Herein, we present the case of an individual with a thoracic spinal cord intramedullary endodermal cyst, which includes glial tissues that achieved gross total resection by surgery.

CASE PRESENTATION

A 59-year-old man presented with a 10-month history of right thigh pain and numbness. Magnetic resonance imaging (MRI) revealed a well-marginated 15-mm cystic lesion at the T7-T8 level. We performed cystectomy and achieved gross total resection. Pathological findings revealed an endodermal cyst, with the presence of glial tissues. No recurrence of cysts was observed upon MRI 2 years after the surgery.

DISCUSSION

Endodermal cyst is defined by pathological findings of a cyst lined by columnar epithelium of presumed endodermal derivation. To date, only 104 reported cases of intramedullary endodermal cysts have been reported; our report was the third case that showed the presence of glial cells in the cyst during pathological examination. Intramedullary cysts are generally difficult to completely resect, with many recurrences. Although we achieved gross total resection, careful follow-up is necessary in the future.

摘要

介绍

脊髓髓内肠源性囊肿是一种罕见的脊髓肿瘤。特别是包含神经胶质组织的肠源性囊肿极为罕见。本文报告了一例胸髓内肠源性囊肿的病例,该囊肿包含神经胶质组织,通过手术实现了大体全切除。

病例介绍

一名 59 岁男性因右大腿疼痛和麻木病史 10 个月就诊。磁共振成像(MRI)显示 T7-T8 水平有一个边界清楚的 15mm 囊肿病变。我们进行了囊肿切除术,实现了大体全切除。病理结果显示为肠源性囊肿,存在神经胶质组织。术后 2 年 MRI 未见囊肿复发。

讨论

肠源性囊肿的定义为病理检查发现囊壁内衬柱状上皮,推测来源于内胚层。迄今为止,仅报道了 104 例脊髓内肠源性囊肿病例;我们的报告是第三个在病理检查中显示囊肿内存在神经胶质细胞的病例。脊髓内囊肿通常难以完全切除,复发率较高。尽管我们实现了大体全切除,但在未来仍需要密切随访。

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