Swanson Sonja A, Eyllon Mara, Sheu Yi-Han, Miller Matthew
Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA
Department of Epidemiology, Erasmus Medical Center, Rotterdam, Netherlands.
Inj Prev. 2020 May 14;27(3):264-70. doi: 10.1136/injuryprev-2019-043605.
Strong and consistent associations between access to firearms and suicide have been found in ecologic and individual-level observational studies. For adolescents, a seminal case-control study estimated that living in a home with (vs without) a firearm was associated with a fourfold increase in the risk of death by suicide.
We use data from a nationally representative study of 10 123 US adolescents aged 13-18 years to (1) measure how much adolescents who live in a home with a firearm differ from those who do not in ways related to their risk of suicide, and (2) incorporate these differences into an updated effect estimate of the risk of adolescent suicide attributable to living in a home with firearms.
Almost one-third (30.7%) of adolescents reported living in a home with firearms. Relative to those who did not, adolescents reporting living in a home with a firearm were slightly more likely to be male, older and reside in the South and rural areas, but few differences were identified for mental health characteristics. The effect size found by Brent and colleagues appeared robust to sources of possible residual confounding: updated relative risks remained above 4.0 across most sensitivity analyses and at least 3.1 in even the most conservative estimates.
Although unmeasured confounding and other biases may nonetheless remain, our updated estimates reinforce the suggestion that adolescents' risk of suicide was increased threefold to fourfold if they had lived in homes with a firearm compared with if they had not.
在生态学和个体层面的观察性研究中,已发现获得枪支与自杀之间存在强烈且一致的关联。对于青少年而言,一项具有开创性的病例对照研究估计,生活在有(而非没有)枪支的家庭中,自杀死亡风险会增加四倍。
我们使用来自一项对10123名13 - 18岁美国青少年的全国代表性研究的数据,以(1)衡量生活在有枪支家庭中的青少年与没有枪支家庭的青少年在与自杀风险相关方面的差异程度,以及(2)将这些差异纳入对因生活在有枪支家庭而导致青少年自杀风险的更新效应估计中。
近三分之一(30.7%)的青少年报告生活在有枪支的家庭中。与没有枪支的青少年相比,报告生活在有枪支家庭中的青少年更有可能是男性、年龄较大且居住在南部和农村地区,但在心理健康特征方面几乎没有发现差异。布伦特及其同事发现的效应大小对可能的残余混杂因素来源似乎具有稳健性:在大多数敏感性分析中,更新后的相对风险仍高于4.0,即使在最保守的估计中也至少为3.1。
尽管仍可能存在未测量的混杂因素和其他偏差,但我们的更新估计强化了这样的观点,即与没有生活在有枪支家庭中的青少年相比,生活在有枪支家庭中的青少年自杀风险增加了三倍至四倍。