Department of Inmunology, University Complutense, School of Medicine, Madrid, Spain.
Department of Inmunology, University Complutense, School of Medicine, Madrid, Spain.
Hum Immunol. 2020 Jul;81(7):321-322. doi: 10.1016/j.humimm.2020.05.002. Epub 2020 May 14.
Quechua Amerindians established Inca Empire and chose Cuzco as their capital. Their language is closely related to that of Aymara ethnic group and both of them were originated from Titikaka Lake Altiplano area. In the present study we have analyzed Bolivian Quechua HLA profile and found that it has common characters with other Andean and Pacific Amerindians (Uros, Aymaras, Lamas, Mapuches, Athabascan), and Pacific Islanders, including Easter Islanders: relatively high frequency of HLA-A24 (:02), class II haplotypes DRB108:02-DQB104:02, and DRB104:03-DQB1* 03:02. Titikaka Lake area prehistoric populations: Quechua, Aymaras and Uros are closely related according to HLA Nei DA genetic distances and other HLA traits: they built up Tiwanaku culture, which resembles that of Easter Island (i.e.: similar giant heads); later, Quechuas also moved to Cuzco. This genetic reletedness together with Easter Island and Titikaka Lake Tiwanaku (Bolivia, Peru) cultural common similarities support a prehistoric Pacific people/Amerindians gene flow.
克丘亚印第安人建立了印加帝国，并选择库斯科作为他们的首都。他们的语言与艾马拉族密切相关，两者都起源于的的喀喀湖高原地区。在本研究中，我们分析了玻利维亚克丘亚人的 HLA 图谱，发现它与其他安第斯和太平洋印第安人（乌鲁斯人、艾马拉人、拉马人、马普切人、阿萨巴斯卡人）以及太平洋岛民，包括复活节岛人，具有共同特征：HLA-A24（:02）、DRB108:02-DQB104:02 和 DRB104:03-DQB1*03:02 类 II 单倍型的频率相对较高。提提卡卡湖地区的史前人口：根据 HLA Nei DA 遗传距离和其他 HLA 特征，克丘亚人、艾马拉人和乌鲁斯人密切相关：他们建立了蒂瓦纳库文化，与复活节岛相似（即：相似的巨型人头）；后来，克丘亚人也搬到了库斯科。这种遗传上的亲缘关系，加上复活节岛和提提卡卡湖的蒂瓦纳库（玻利维亚、秘鲁）文化的共同相似之处，支持了史前太平洋人与美洲印第安人之间的基因流动。
