Department of Surgery, Firoozgar Clinical Research Development Center (FCRDC), Iran University of Medical Sciences (IUMS), Tehran, Iran.
Firoozgar Clinical Research Development Center (FCRDC), Iran University of Medical Sciences (IUMS), Tehran, Iran.
J Invest Surg. 2021 Oct;34(10):1083-1088. doi: 10.1080/08941939.2020.1767734. Epub 2020 May 18.
Obstructive defecation syndrome (ODS) affects quality of life of patients to a great extent by disturbing defecation. Laparoscopic ventral mesh rectopexy (LVMR) has gained much attention in the recent years. Common synthetic used meshes have a risk of erosion for adjacent pelvic organs leading to some complications. The aim of this study was to assess the outcomes of LVMR using polyvinylidene fluoride (PVDF) mesh in patients with ODS for the first time. In this experimental study, patients with a history of ODS and associated signs and symptoms such as descending perineum, rectocele, enterocele, intussusception, rectal prolapse or a combined disorder were recruited. The patients underwent LVMR using a PVDF mesh. They were followed using the Constipation Scoring System (CSS) score. Participants were followed up for 12 months after surgery. Complications and CSS for each patient and its changes were the main outcomes of this study.
Of 156 patients, 155 had a 12-month complete follow-up. Thirty-nine (25.2%) were male and 116 (74.8%) female. Mean ± SD age of participants was 45.61 ± 14.02 years. The overall complication rate was 3.87%. No major mesh-related complications were recorded. Four cases (2.58%) of trocar site hernia were reported. Also, two cases (1.29%) of postoperative bleeding occurred. CSS before the operation and 1, 3, and 12 months after it were 11.04 ± 5.93, 7.98 ± 4.85, 5.46 ± 3.70 and 4.09 ± 2.98, respectively ( < 0.001).
Synthetic meshes might cause severe erosion in pelvic organs. However, at least in short-term follow-up, PVDF mesh seems to be safe and effective in LVMR, with the advantage of being cheaper.
梗阻性排便障碍综合征(ODS)通过扰乱排便极大地影响了患者的生活质量。腹腔镜腹侧网片直肠固定术(LVMR)近年来受到了广泛关注。常用的合成材料网片有侵蚀相邻盆腔器官的风险,导致一些并发症。本研究的目的是首次评估使用聚偏二氟乙烯(PVDF)网片行 LVMR 治疗 ODS 患者的疗效。在这项实验研究中,我们招募了有 ODS 病史且有会阴下降、直肠前突、乙状结肠疝、套叠、直肠脱垂或混合性疾病等相关症状和体征的患者。患者接受了使用 PVDF 网片的 LVMR。通过便秘评分系统(CSS)评分对患者进行随访。术后 12 个月对患者进行随访。本研究的主要观察指标为每位患者的并发症和 CSS 评分及其变化。
156 例患者中,155 例完成了 12 个月的完整随访。39 例(25.2%)为男性,116 例(74.8%)为女性。参与者的平均年龄为 45.61±14.02 岁。总的并发症发生率为 3.87%。无严重与网片相关的并发症。报告了 4 例(2.58%)经套管部位疝,2 例(1.29%)术后出血。术前、术后 1、3、12 个月的 CSS 分别为 11.04±5.93、7.98±4.85、5.46±3.70、4.09±2.98( < 0.001)。
合成网片可能导致盆腔器官严重侵蚀。然而,至少在短期随访中,PVDF 网片在 LVMR 中是安全有效的,且具有价格优势。