Stages or phenotypes? A critical look at COVID-19 pathophysiology.
作者信息
Jain Amit, Doyle D John
机构信息
Anesthesiology Institute, Cleveland Clinic Abu Dhabi, Al Maryah Island, Abu Dhabi, United Arab Emirates.
出版信息
Intensive Care Med. 2020 Jul;46(7):1494-1495. doi: 10.1007/s00134-020-06083-6. Epub 2020 May 18.
Abstract
摘要
相似文献
1
Stages or phenotypes? A critical look at COVID-19 pathophysiology.阶段还是表型？对新冠病毒病理生理学的批判性审视。
Intensive Care Med. 2020 Jul;46(7):1494-1495. doi: 10.1007/s00134-020-06083-6. Epub 2020 May 18.
2
COVID-19 phenotypes: leading or misleading?COVID-19 表型：主导还是误导？
Eur Respir J. 2020 Aug 27;56(2). doi: 10.1183/13993003.02195-2020. Print 2020 Aug.
3
Lockdown-type measures look effective against covid-19.封锁类措施看起来对新冠病毒有效。
BMJ. 2020 Jul 15;370:m2809. doi: 10.1136/bmj.m2809.
4
COVID-19 Phenotypes and Potential Harm of Conventional Treatments: How to Prove the Hypothesis.COVID-19的表型及传统治疗的潜在危害：如何验证这一假设。
Am J Respir Crit Care Med. 2020 Aug 15;202(4):619-621. doi: 10.1164/rccm.202004-1293LE.
5
Identifying phenotypes of COVID-19, defining their pathogenesis, and targeting treatments could improve outcomes.识别新冠病毒疾病（COVID-19）的表型，明确其发病机制，并针对性地进行治疗，可能会改善治疗结果。
Respir Physiol Neurobiol. 2020 Sep;280:103477. doi: 10.1016/j.resp.2020.103477. Epub 2020 Jun 24.
6
Novel Phenotypes in Respiratory Failure: Same As It Ever Was.呼吸衰竭的新表型：一如既往。
Am J Respir Crit Care Med. 2020 Nov 1;202(9):1207-1209. doi: 10.1164/rccm.202008-3322ED.
7
The Respiratory Drive: An Overlooked Tile of COVID-19 Pathophysiology.呼吸驱动：新冠病毒病理生理学中被忽视的一个方面
Am J Respir Crit Care Med. 2020 Oct 15;202(8):1079-1080. doi: 10.1164/rccm.202008-3142ED.
8
Call for Papers: The Pathophysiology of COVID-19 and SARS-CoV-2 Infection.征文启事：新型冠状病毒肺炎及严重急性呼吸综合征冠状病毒2感染的病理生理学
Am J Physiol Lung Cell Mol Physiol. 2020 May 1;318(5):L1016-L1019. doi: 10.1152/ajplung.00136.2020. Epub 2020 Apr 8.
9
COVID-19 Ventilatory Phenotypes and Obesity: Is There a Relationship?新冠病毒肺炎通气表型与肥胖：存在关联吗？
Obesity (Silver Spring). 2020 Aug;28(8):1370. doi: 10.1002/oby.22877. Epub 2020 Jul 10.
10
Audio Interview: A Look at SARS-CoV-2 Transmission.音频访谈：审视新冠病毒传播情况。
N Engl J Med. 2020 Jun 18;382(25):e112. doi: 10.1056/NEJMe2022576.
引用本文的文献
1
Impact of immunosuppressive therapy on pulmonary perfusion in kidney transplant recipients after COVID-19 illness.免疫抑制治疗对新冠病毒感染康复后肾移植受者肺灌注的影响。
Front Med (Lausanne). 2025 Jun 11;12:1562407. doi: 10.3389/fmed.2025.1562407. eCollection 2025.
2
Using Trajectories of Bedside Vital Signs to Identify COVID-19 Subphenotypes.利用床边生命体征轨迹识别新冠病毒疾病亚表型
Chest. 2024 Mar;165(3):529-539. doi: 10.1016/j.chest.2023.09.020. Epub 2023 Sep 23.
3
Interpretable clinical phenotypes among patients hospitalized with COVID-19 using cluster analysis.使用聚类分析对COVID-19住院患者的可解释临床表型进行研究。
Front Digit Health. 2023 Apr 11;5:1142822. doi: 10.3389/fdgth.2023.1142822. eCollection 2023.
4
COVID-19 Phenotypes and Comorbidity: A Data-Driven, Pattern Recognition Approach Using National Representative Data from the United States.COVID-19 表型和合并症：一种使用来自美国的全国代表性数据进行数据驱动、模式识别的方法。
Int J Environ Res Public Health. 2022 Apr 12;19(8):4630. doi: 10.3390/ijerph19084630.
5
Mortality and Pulmonary Embolism in Acute Respiratory Distress Syndrome From COVID-19 vs. Non-COVID-19.新型冠状病毒肺炎与非新型冠状病毒肺炎所致急性呼吸窘迫综合征的死亡率及肺栓塞情况
Front Med (Lausanne). 2022 Mar 4;9:800241. doi: 10.3389/fmed.2022.800241. eCollection 2022.
6
Point of care ultrasound: a clinical decision support tool for COVID-19.即时超声：COVID-19 的临床决策支持工具。
Singapore Med J. 2023 Apr;64(4):226-236. doi: 10.11622/smedj.2021098.
7
Olfactory Nasal Nitric Oxide Link in COVID-19: A Marker of Neurogenesis or Risk Factor for Chronic Rhinosinusitis?新型冠状病毒肺炎中的嗅觉、鼻腔一氧化氮关联：神经发生的标志物还是慢性鼻-鼻窦炎的危险因素？
Am J Respir Crit Care Med. 2021 Dec 1;204(11):1345-1347. doi: 10.1164/rccm.202107-1697LE.
8
Development and Validation of ARC, a Model for Anticipating Acute Respiratory Failure in Coronavirus Disease 2019 Patients.ARC的开发与验证：一种预测2019冠状病毒病患者急性呼吸衰竭的模型
Crit Care Explor. 2021 Jun 4;3(6):e0441. doi: 10.1097/CCE.0000000000000441. eCollection 2021 Jun.
9
"Mosaic Perfusion Pattern" on Dual-Energy CT in COVID-19 Pneumonia: Pulmonary Vasoplegia or Vasoconstriction?新型冠状病毒肺炎双能CT上的“马赛克灌注模式”：肺血管麻痹还是血管收缩？
Radiol Cardiothorac Imaging. 2020 Sep 10;2(5):e200433. doi: 10.1148/ryct.2020200433. eCollection 2020 Oct.
10
Endothelialitis plays a central role in the pathophysiology of severe COVID-19 and its cardiovascular complications.内皮细胞炎在重症 COVID-19 及其心血管并发症的病理生理学中起着核心作用。
Acta Cardiol. 2021 Apr;76(2):109-124. doi: 10.1080/00015385.2020.1846921. Epub 2020 Nov 19.
本文引用的文献
1
COVID-19 pneumonia: different respiratory treatments for different phenotypes?新冠肺炎：针对不同表型采用不同的呼吸治疗方法？
Intensive Care Med. 2020 Jun;46(6):1099-1102. doi: 10.1007/s00134-020-06033-2. Epub 2020 Apr 14.
2
Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.《武汉 2019 年新型冠状病毒感染的肺炎 138 例住院患者临床特征分析》
JAMA. 2020 Mar 17;323(11):1061-1069. doi: 10.1001/jama.2020.1585.
3
A Novel Coronavirus from Patients with Pneumonia in China, 2019.2019 年中国肺炎患者中的一种新型冠状病毒。
N Engl J Med. 2020 Feb 20;382(8):727-733. doi: 10.1056/NEJMoa2001017. Epub 2020 Jan 24.
4
ACE2 as therapy for pulmonary arterial hypertension: the good outweighs the bad.血管紧张素转换酶2作为肺动脉高压的治疗手段：利大于弊。
Eur Respir J. 2018 Jun 21;51(6). doi: 10.1183/13993003.00848-2018. Print 2018 Jun.
5
The pulmonary endothelium in acute respiratory distress syndrome: insights and therapeutic opportunities.急性呼吸窘迫综合征中的肺血管内皮：深入了解和治疗机会。
Thorax. 2016 May;71(5):462-73. doi: 10.1136/thoraxjnl-2015-207461. Epub 2016 Mar 11.
Zotero 插件