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何时考虑在后外侧降主动脉固定术之外再进行后路气管固定术以治疗有症状的气管支气管软化症。

When to consider a posterolateral descending aortopexy in addition to a posterior tracheopexy for the surgical treatment of symptomatic tracheobronchomalacia.

机构信息

Department of Surgery, Boston Children's Hospital, Boston, MA.

Division of Pulmonary Medicine, Boston Children's Hospital, Boston, MA.

出版信息

J Pediatr Surg. 2020 Dec;55(12):2682-2689. doi: 10.1016/j.jpedsurg.2020.04.018. Epub 2020 May 3.

Abstract

PURPOSES

The descending thoracic aorta typically crosses posterior to the left mainstem bronchus (LMSB). We sought to evaluate patient factors that may lead one to consider a posterolateral descending thoracic aortopexy (PLDA) in addition to a posterior tracheopexy (PT) in the surgical treatment of symptomatic tracheobronchomalacia (TBM) that involves the LMSB.

METHODS

Retrospective review of patients who underwent PT with or without PLDA between 2012 and 2017. Severity and extent of TBM were assessed using dynamic tracheobronchoscopy. Aortic positioning compared to the anterior border of the spine (ABS) at the level of the left mainstem bronchus was identified on computed tomography (CT). Factors associated with performing a PLDA were evaluated with logistic regression.

RESULTS

Of 188 patients who underwent a PT, 70 (37%) also had a PLDA performed. On multivariate analysis, >50% LMSB compression on bronchoscopy (OR 8.06, p < 0.001), >50% of the aortic diameter anterior to the ABS (OR 2.06, p = 0.05), and more recent year of surgery (OR 1.61, p = 0.003) were associated with performing a PLDA.

CONCLUSION

When performing a PT, a PLDA should be considered for patients who have >50% LMSB compression on dynamic bronchoscopy, and in those with a descending thoracic aorta located >50% anterior to the ABS.

LEVEL OF EVIDENCE

III TYPE OF STUDY: Retrospective comparative study.

摘要

目的

降主动脉通常位于左主支气管(LMSB)后方。我们旨在评估患者的一些因素,这些因素可能会促使人们在治疗涉及 LMSB 的有症状的气管支气管软化症(TBM)时,除了进行后外侧降主动脉固定术(PLDA)外,还考虑进行后外侧气管固定术(PT)。

方法

回顾性分析了 2012 年至 2017 年间接受 PT 加或不加 PLDA 的患者。使用动态气管支气管镜检查评估 TBM 的严重程度和范围。在 CT 上确定降主动脉相对于左主支气管水平的脊柱前边界(ABS)的位置。使用逻辑回归评估与进行 PLDA 相关的因素。

结果

在 188 例接受 PT 的患者中,70 例(37%)还进行了 PLDA。多因素分析显示,支气管镜检查时 LMSB 受压>50%(OR 8.06,p<0.001)、主动脉直径的前 ABS 大于>50%(OR 2.06,p=0.05)和手术时间较晚(OR 1.61,p=0.003)与进行 PLDA 相关。

结论

在行 PT 时,如果患者的动态支气管镜检查显示 LMSB 受压>50%,或者降主动脉位于 ABS 前>50%,则应考虑进行 PLDA。

证据水平

III 型研究:回顾性比较研究。

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