社论评论:基于文石的骨软骨缺损植入物——珊瑚能让老山羊再次奔跑吗?
Editorial Commentary: Aragonite-Based Implants for Osteochondral Defects-Could Coral Make Old Goats Run Again?
机构信息
Weill-Cornell Medical College.
出版信息
Arthroscopy. 2020 Jul;36(7):1895-1896. doi: 10.1016/j.arthro.2020.05.011. Epub 2020 May 20.
The population of patients with early arthritis remains a treatment challenge because of the specifics of their disease (diffuse chondrosis rather than focal defect, frequent associated morbidities such as instability or meniscal deficiency) and where they are in life (young, active, working). Too young with "not enough damage" for arthroplasty but frequently unresponsive to conservative care, they are in the midst of life yet functionally quite limited. The next generation of non-arthroplasty implants is being investigated to potentially bridge this treatment gap and provide relief for the ever-growing number of young patients with arthritis.
早期关节炎患者的人群仍然是一个治疗挑战,因为他们的疾病具有特殊性(弥漫性软骨病而不是局灶性缺陷,频繁伴有诸如不稳定或半月板缺失等相关疾病),并且他们处于人生的某个阶段(年轻、活跃、工作中)。对于关节置换术来说,他们太年轻且“损伤不足”,但经常对保守治疗反应不佳,他们正处于人生的黄金时期,但功能却受到了极大的限制。下一代非关节置换植入物正在被研究,以潜在地弥补这一治疗空白,并为越来越多的年轻关节炎患者提供缓解。