Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup.
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Curr Opin Rheumatol. 2020 Jul;32(4):357-364. doi: 10.1097/BOR.0000000000000718.
MRI has, as the only imaging modality, the ability to visualize both the inflammatory and destructive aspects of sacroiliitis and is a crucial element in the diagnosis and classification of axial spondyloarthritis (axSpA). However, the MRI appearance of several potential differential diagnoses may resemble axSpA sacroiliitis.
The appearances of sacroiliac joint (SIJ) MRIs of various diseased and healthy populations have recently been intensively studied. BME, the key requirement in the Assessment of Spondyloarthritis international Society (ASAS) definition of a 'MRI positive of sacroiliitis' may also be found in degenerative disease, athletes and healthy persons, and, particularly, postpartum women. Certain pattern of BME (high extent, large depth from articular surface, close relation to other lesion types) as well as the presence of structural lesions, particularly bone erosion, backfill or ankylosis increase the likelihood/specificity of being axSpA. Furthermore, old and novel MRI approaches to best distinguish the sacroiliitis of early axSpA from differential diagnoses have recently been tested and compared.
Significant new and clinically relevant knowledge has been gained, but further research is still needed to optimally distinguish what is and what isn't sacroiliitis.
磁共振成像(MRI)是唯一能够同时显示炎症和破坏的影像学手段,是诊断和分类中轴型脊柱关节炎(axSpA)的关键要素。然而,几种潜在的鉴别诊断的 MRI 表现可能与 axSpA 骶髂关节炎相似。
最近,人们对各种疾病和健康人群的骶髂关节(SIJ)MRI 表现进行了深入研究。骨髓水肿(BME)是评估脊柱关节炎国际协会(ASAS)定义的“骶髂关节炎 MRI 阳性”的关键要求,也可见于退行性疾病、运动员和健康人群,尤其是产后妇女。BME 的特定模式(广泛程度、距关节表面的深度大、与其他病变类型密切相关)以及结构病变的存在,特别是骨侵蚀、填补或强直,增加了 axSpA 的可能性/特异性。此外,最近还测试和比较了新的和新颖的 MRI 方法,以最佳地区分早期 axSpA 的骶髂关节炎与鉴别诊断。
已经获得了重要的新知识,但仍需要进一步研究以最佳地区分什么是骶髂关节炎,什么不是骶髂关节炎。