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改良小关节融合术治疗腰椎退行性疾病:491例患者的融合技术、临床疗效及融合率病例系列研究

Modified Facet Joint Fusion for Lumbar Degenerative Disease: Case Series of a Fusion Technique, Clinical Outcomes, and Fusion Rate in 491 Patients.

作者信息

Ren Zhinan, Li Zheng, Li Shugang, Xu Derong, Chen Xin

机构信息

Department of Orthopaedics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Department of Orthopaedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

出版信息

Oper Neurosurg. 2020 Sep 1;19(3):255-263. doi: 10.1093/ons/opaa147.

Abstract

BACKGROUND

Controversy still exists regarding the optimal fusion technique for the treatment of unstable lumbar spondylolisthesis.

OBJECTIVE

To evaluate the safety and efficacy of modified facet joint fusion (MFF).

METHODS

A total of 491 patients with unstable lumbar spondylolisthesis who underwent MFF were retrospectively reviewed. Computed tomography was used to evaluate the fusion rate of MFF at 6- and 12-mo follow-up postoperatively. Clinical outcomes included visual analog scale pain scores for low back pain (VAS-LBP) and leg pain (VAS-LP), Japanese Orthopedic Association scores (JOA), and Oswestry Disability Index (ODI), all of which were obtained preoperatively and postoperatively at 1-, 3-, 6-, and 12-mo follow-up times. The clinical outcomes were determined to be excellent, good, fair, or poor according to the MacNab classification at the last follow-up time.

RESULTS

Of the 491 patients, the fusion rates at the 6-mo and 1-yr follow-up were 56.8% and 96.1%, respectively. Between baseline and 1-yr follow-up time, VAS-LP and VAS-LBP improved from 5.6 ± 0.9 to 0.4 ± 0.5 and 5.1 ± 1.2 to 1.5 ± 0.9, respectively (P < .001). JOA improved from 9.0 ± 2.0 to 27.7 ± 1.0, and ODI decreased from 64.0 ± 2.0 to 19 ± 1.0 (P < .001). At the final evaluation, 93.6% patients showed excellent or good results, and 3.2% showed fair results. There were no MFF technique-related complications.

CONCLUSION

MFF technique achieved satisfactory clinical outcomes and fusion rate and appears to be a promising alternative fusion technique for the treatment of unstable lumbar spondylolisthesis.

摘要

背景

关于不稳定腰椎滑脱症治疗的最佳融合技术仍存在争议。

目的

评估改良小关节融合术(MFF)的安全性和有效性。

方法

回顾性分析491例行MFF治疗的不稳定腰椎滑脱症患者。采用计算机断层扫描评估术后6个月和12个月时MFF的融合率。临床结果包括腰痛视觉模拟评分(VAS-LBP)、腿痛视觉模拟评分(VAS-LP)、日本骨科协会评分(JOA)和Oswestry功能障碍指数(ODI),均在术前及术后1、3、6和12个月随访时获取。根据末次随访时的MacNab分类,将临床结果判定为优、良、可或差。

结果

491例患者中,6个月和1年随访时的融合率分别为56.8%和96.1%。在基线和1年随访期间,VAS-LP从5.6±0.9改善至0.4±0.5,VAS-LBP从5.1±1.2改善至1.5±0.9(P<.001)。JOA从9.0±2.0提高至27.7±1.0,ODI从64.0±2.0降至19±~1.0(P<.001)。在最终评估中,93.6%的患者显示优或良的结果,3.2%的患者显示可的结果。未出现与MFF技术相关的并发症。

结论

MFF技术取得了满意的临床结果和融合率,似乎是治疗不稳定腰椎滑脱症的一种有前景的替代融合技术。

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