College of Human Medicine, Michigan State University, East Lansing, MI, USA.
Department of Family Medicine, College of Human Medicine, Michigan State University, 788 Service Rd, East Lansing, MI, USA.
Drug Alcohol Depend. 2020 Jul 1;212:108035. doi: 10.1016/j.drugalcdep.2020.108035. Epub 2020 May 15.
The aim of the current study is to estimate cannabis use prevalence among individuals with diabetes participating in the United States (US) National Survey on Drug Use and Health (NSDUH), 2005-2018. Plausible biological mechanisms link cannabis use and metabolic regulation. Cannabis use can also alter perception and adherence to treatment especially among patients with insulin-dependent diabetes.
The NSDUH is designed to select and recruit, annually, a representative sample of the non-institutionalized US population (12+ years). Computer-assisted self-interviews gathered information on cannabis use. The current study sample included 30,915 participants who self-reported a physician diagnosis of diabetes.
Prevalence of past 30-day cannabis use increased 340% among individuals with diabetes, from 1.7% (95% confidence interval [CI] = 1.1, 2.6) in 2005 to 5.8% (95% CI = 4.7, 7.1) in 2018. Results from the logistic regression model indicated that this increase was robust (odds ratio of cannabis use per NSDUH year = 1.13; 95% CI = 1.10, 1.15). The increase was observed among different sociodemographic subgroups and in states with or without medical cannabis laws.
As cannabis use prevalence increases, screening for use among diabetes patients is needed to optimize outcomes and reduce potential adverse effects.
本研究旨在估计参与美国国家药物使用与健康调查（NSDUH）的糖尿病患者的大麻使用流行率，时间跨度为 2005 年至 2018 年。一些合理的生物学机制将大麻使用与代谢调节联系起来。大麻的使用还可能改变患者对治疗的感知和坚持，尤其是那些依赖胰岛素治疗的糖尿病患者。
NSDUH 旨在每年选择和招募非机构化的美国人群（12 岁以上）作为代表性样本。计算机辅助的自我访谈收集了关于大麻使用的数据。本研究的样本包括 30915 名自我报告有医生诊断为糖尿病的参与者。
糖尿病患者过去 30 天的大麻使用流行率增加了 340%，从 2005 年的 1.7%（95%置信区间 [CI] = 1.1，2.6）增加到 2018 年的 5.8%（95% CI = 4.7，7.1）。逻辑回归模型的结果表明，这种增加是稳健的（大麻使用的每 NSDUH 年的比值比 = 1.13；95% CI = 1.10，1.15）。这种增加在不同的社会人口统计学亚组和有或没有医用大麻法律的州都有观察到。
随着大麻使用流行率的增加，需要对糖尿病患者进行使用筛查，以优化治疗结果并减少潜在的不良反应。
