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创新性定制髂嵴骨块结合改良颈椎网笼作为钢板治疗 C2 椎体骨巨细胞瘤

Management of C2 Body Giant Cell Tumor by Innovatively Fashioned Iliac Crest Graft and Modified Cervical Mesh Cage Used as Plate.

机构信息

Department of Neurosurgery, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.

Department of Neurosurgery, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.

出版信息

World Neurosurg. 2020 Aug;140:241-246. doi: 10.1016/j.wneu.2020.05.182. Epub 2020 May 27.

Abstract

BACKGROUND

Locally aggressive vertebral body tumors of the axis must be treated with wide local excision for best outcome. Reconstruction of the load-bearing vertebra needs to be done after tumor resection in such a manner so as to give stable, long-term fusion in this young population.

METHODS

We describe the management strategy of a 25-year-old acutely quadriplegic patient, with respiratory distress, with a C2 giant cell tumor. The use of a novel iliac crest graft modification used for C2 reconstruction along with a modified mesh cage used as an anterior plate has been reported.

RESULTS

The patient had a good outcome at 18 months' follow-up, with neurologic improvement and a solid fusion.

CONCLUSIONS

Iliac crest autograft is inexpensive and easy to harvest and can be considered as a C2 prosthesis, especially in a resource-constrained setting. Modified iliac crest graft can be used for load transmission from C1 lateral mass to C3 body, and the mesh cage can be modified according to need as a plate with good results in an emergency.

摘要

背景

轴部局部侵袭性椎体肿瘤必须通过广泛的局部切除来获得最佳疗效。在这种年轻人群中,为了获得稳定、长期的融合,需要在肿瘤切除后对承重椎体进行重建。

方法

我们描述了一名 25 岁急性四肢瘫痪患者的治疗策略,该患者患有 C2 巨细胞瘤,伴有呼吸窘迫。报告了一种新型髂嵴移植物改良物用于 C2 重建,以及一种改良的网笼作为前路板的应用。

结果

患者在 18 个月的随访中取得了良好的结果,神经功能改善,融合牢固。

结论

髂嵴自体移植物价格低廉,易于获取,可作为 C2 假体,特别是在资源有限的情况下。改良的髂嵴移植物可用于将 C1 侧块的负荷传递到 C3 体,并且可以根据需要将网笼修改为具有良好效果的板。

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