School of Orthodontics, Department of Neurosciences, Reproductive Sciences and Oral Sciences, University of Naples Federico II, Naples, Italy.
Department of Translational Medicine, University Naples Federico II, Naples, Italy.
J Oral Rehabil. 2020 Aug;47(8):944-950. doi: 10.1111/joor.13024. Epub 2020 Jun 28.
Juvenile idiopathic arthritis (JIA) is an autoimmune, chronic, inflammatory joint disease, affecting children and adolescents. Patients with JIA may have pain and fatigue in muscles. There are not studies evaluating the pressure pain thresholds (PPTs) of both masticatory muscles and temporomandibular joint (TMJ) in patients with JIA.
This study aimed to investigate PPTs of masticatory muscles and TMJ in subjects with JIA.
Fifty-one JIA patients and fifty-two healthy subjects were recruited. JIA group was assessed for with a standardised clinical examination for temporomandibular disorders. In all subjects, the PPT was evaluated in the following sites: anterior temporalis (AT) and masseter (MM) muscles, TMJ and thenar (TH) eminence. Comparisons between groups were assessed with unpaired t test and ANOVA (P < .05).
Pressure pain thresholds were significantly lower among JIA patients compared with controls (P < .001) for all analysed sites. The presence of TMJ pain at palpation was significantly associated with a lower PPT at TMJ (P = .031).
Patients with JIA have generally lowered pain threshold to mechanical stimulus, which suggests an effect of JIA on nocicepton-modulating processes.
幼年特发性关节炎（JIA）是一种影响儿童和青少年的自身免疫性、慢性、炎症性关节疾病。JIA 患者可能会出现肌肉疼痛和疲劳。目前还没有研究评估 JIA 患者咀嚼肌和颞下颌关节（TMJ）的压力疼痛阈值（PPT）。
本研究旨在探讨 JIA 患者咀嚼肌和 TMJ 的 PPT。
招募了 51 名 JIA 患者和 52 名健康受试者。对 JIA 组进行了颞下颌关节紊乱的标准临床检查。在所有受试者中，评估了以下部位的 PPT：前颞肌（AT）和咬肌（MM）、TMJ 和大鱼际（TH）隆起。采用独立样本 t 检验和 ANOVA 对组间进行比较（P<.05）。
与对照组相比，JIA 患者的所有分析部位的压力疼痛阈值均显著降低（P<.001）。TMJ 触诊疼痛的存在与 TMJ 较低的 PPT 显著相关（P=.031）。
JIA 患者对机械刺激的疼痛阈值普遍降低，这表明 JIA 对伤害感受调制过程有影响。
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