经颅多普勒超声检测缺血性卒中的影响：一项系统评价与荟萃分析方案
Impact of transcranial Doppler sonography for detecting ischemic stroke: A protocol of systematic review and meta-analysis.
作者信息
Liu Wen-Juan, Zhang Ya-Juan
机构信息
Department of Neurology, First Affiliated Hospital of Jiamusi University, Jiamusi, China.
出版信息
Medicine (Baltimore). 2020 May 29;99(22):e20451. doi: 10.1097/MD.0000000000020451.
BACKGROUND
This study aims to explore the impact of transcranial Doppler sonography (TDS) for detecting ischemic stroke (IS).
METHODS
PUBMED, EMBASE, Cochrane Library, PsycINFO, Cumulative Index to Nursing and Allied Health Literature, Allied and Complementary Medicine Database, WANGFANG, Chinese Biomedical Literature Database, and China National Knowledge In-frastructure will be utilized to examine case-controlled studies that used TDS for detecting IS. All electronic databases will be searched from inception to March 20, 2020. All study selection, data extraction, and study quality assessment will be carried out by 2 independent reviewers. All study quality will be assessed by Quality Assessment of Diagnostic Accuracy Studies tool, and statistical analysis will be performed by RevMan V.5.3 software and Stata V.12.0 software.
RESULTS
This study will explore the impact of TDS for detecting IS through sensitivity, specificity, positive and negative likelihood ratio, and diagnostic odds ratio.
CONCLUSION
This study expects to find out whether TDS can be utilized for IS detection.Systematic review registration: INPLASY202040155.
背景
本研究旨在探讨经颅多普勒超声（TDS）对检测缺血性卒中（IS）的影响。
方法
将利用PUBMED、EMBASE、Cochrane图书馆、PsycINFO、护理学与健康相关文献累积索引、补充与替代医学数据库、万方数据库、中国生物医学文献数据库和中国知网，检索使用TDS检测IS的病例对照研究。所有电子数据库将从建库至2020年3月20日进行检索。所有研究的筛选、数据提取和研究质量评估将由2名独立的评审员进行。所有研究质量将通过诊断准确性研究的质量评估工具进行评估，统计分析将使用RevMan V.5.3软件和Stata V.12.0软件进行。
结果
本研究将通过敏感性、特异性、阳性和阴性似然比以及诊断比值比探讨TDS对检测IS的影响。
结论
本研究期望查明TDS是否可用于IS检测。系统评价注册：INPLASY202040155。
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