The Wolffian ducts, or mesonephric ducts, are paired embryonic structures that serve as progenitors of the male internal genitalia and are involved in the incipient development of the renal system in both sexes. The Wolffian ducts (WDs) develop in male and female embryos but are only maintained in males by testosterone, and they give rise to the epididymis, vas deferens, and seminal vesicles. Although the development of the WDs into the male internal genitalia is dependent on testosterone, there is a dynamic and complex interplay of androgens, growth factors, gene expression in the duct epithelium, and mesenchyme for the proper formation of the male reproductive tract.
沃尔夫管，又称中肾管，是成对的胚胎结构，是男性内生殖器的前身，并且参与两性泌尿系统的早期发育。沃尔夫管在雄性和雌性胚胎中都有发育，但只有在雄性胚胎中，睾酮才能维持其发育，它会发育成附睾、输精管和精囊。虽然沃尔夫管发育成男性内生殖器依赖于睾酮，但雄激素、生长因子、导管上皮和间充质中的基因表达之间存在动态且复杂的相互作用，以确保男性生殖道的正常形成。
