[舒他西林颗粒在儿科患者中的应用经验]
[Experiences with sultamicillin granules in pediatric patients].
作者信息
Iguchi K, Kamiya H, Sakurai M, Shimizu S, Nishi H, Kawaguchi H, Yoshizumi T, Inoue M, Kojima M
机构信息
Department of Pediatrics, School of Medicine, Mie University.
出版信息
Jpn J Antibiot. 1988 Dec;41(12):1906-13.
Sultamicillin (SBTPC) is a combination drug of sulbactam (SBT) and ampicillin (ABPC) in an ester bonding at 1:1 ratio. SBT, a new semisynthetic beta-lactamase inhibitor restores and extends the spectrum of ABPC against resistant strains of bacteria. SBTPC granules were administered to 26 pediatric patients with infections, and clinical efficacies were studied in 23 patients. The clinical efficacy rate was 95.7% and the drug was evaluated to be highly effective for the treatment of infectious diseases in the pediatric field. SBTPC was safe and well tolerated.
舒他西林（SBTPC）是一种由舒巴坦（SBT）和氨苄西林（ABPC）以1:1酯键结合而成的复方药物。SBT是一种新型半合成β-内酰胺酶抑制剂，可恢复并扩大ABPC对耐药菌株的抗菌谱。对26例感染性儿科患者给予舒他西林颗粒剂治疗，并对其中23例患者的临床疗效进行了研究。临床有效率为95.7%，该药物被评估对儿科领域的传染病治疗非常有效。舒他西林安全且耐受性良好。
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