González-Darder José M, Capilla-Guasch Pau, Real-Peña Luis
Department of Neurosurgery, Hospital Clínico Universitario, Valencia, Spain.
J Neurol Surg B Skull Base. 2020 Jun;81(3):223-231. doi: 10.1055/s-0039-1685536. Epub 2019 Apr 23.
The main objective of this article is to describe a simple and safe protocol for the microsurgical management of ventrally located intrinsic pontomedullary lesions based on the retrosigmoid approach, cortectomy performed utilizing safe entry zones of the pons and medulla, and a delicate microsurgical resection. The intraoperative protocol includes redundant procedures that provide security in decision-making during surgery. A prospective series of 11 cases is presented. All patients were studied following the same clinical and imaging workup. A regular retrosigmoid craniotomy surgical approach was utilized. The peritrigeminal area in the pons and the olivary area in the medulla were considered as the safe entry zones. Neuronavigation of the white fiber tracts and electrophysiological monitoring were used as intraoperative aids to locate the lesions, the safe entry zones, and the placement of the cortectomy. Six lesions were pontine, two medullary, and the remaining six pontomedullary. Eight lesions were cavernomas, while the remaining three tumors. Overall, we obtained a postoperative functional improvement in the affected cranial nerves in 90.1% of the patients and a total or partial recovery of long ascending or descending pathway symptoms in 72.3% of the patients. All the patients were satisfied with the procedure and the results. Radical resection of ventral intrinsic pontomedullary lesions displays a high degree of intraoperative reliability, and a good clinical result is possible using simple surgical procedures. The anatomical references are the first element in the decision-making process during surgery.
本文的主要目的是描述一种基于乙状窦后入路、利用脑桥和延髓的安全入路区域进行皮质切除术以及精细显微手术切除的简单且安全的显微手术方案,用于处理位于腹侧的脑桥延髓内部病变。术中方案包括一些冗余步骤,这些步骤可在手术过程中的决策制定方面提供保障。
本文呈现了一个包含11例患者的前瞻性系列研究。所有患者均接受了相同的临床和影像学检查。采用常规的乙状窦后开颅手术入路。将脑桥的三叉神经周围区域和延髓的橄榄区域视为安全入路区域。术中利用白质纤维束的神经导航和电生理监测来定位病变、安全入路区域以及确定皮质切除术的位置。
6个病变位于脑桥,2个位于延髓,其余6个为脑桥延髓病变。8个病变为海绵状血管瘤,其余3个为肿瘤。总体而言,90.1%的患者患侧颅神经功能在术后得到改善,72.3%的患者长升或长降通路症状完全或部分恢复。所有患者对手术过程和结果均感到满意。
腹侧脑桥延髓内部病变的根治性切除在术中具有高度可靠性,采用简单的手术操作即可取得良好的临床效果。解剖学参考是手术决策过程中的首要因素。