New York University Langone Medical Center, New York, NY.
New York University Langone Medical Center, New York, NY.
Urology. 2021 May;151:37-43. doi: 10.1016/j.urology.2020.05.034. Epub 2020 Jun 3.
The implications of estrogen depletion on the lower urinary tract and vagina are relevant to the urologist treating women with genitourinary symptoms. The main symptoms of vaginal estrogen depletion that affect women are dyspareunia and vaginal dryness, recurrent urinary tract infection, and lower urinary tract symptoms. Vaginal estrogen can be used to effectively treat these conditions. Vaginal estrogen is available in a variety of formulations. Each formulation has different considerations regarding its use and patients should be actively involved in choosing the right product for them. Contrary to concerns over the risks of oral estrogen, vaginal estrogen has a low-risk profile. In terms of contra-indications for use, there are relatively few absolute contraindications for vaginal estrogen. A thorough understanding of vaginal estrogen's safety, efficacy and correct use is essential to the urologist treating the post-menopausal female.
雌激素缺乏对下尿路和阴道的影响与治疗女性泌尿生殖系统症状的泌尿科医生有关。阴道雌激素缺乏影响女性的主要症状是性交痛和阴道干燥、复发性尿路感染和下尿路症状。阴道雌激素可有效治疗这些疾病。阴道雌激素有多种制剂。每种制剂在使用方面都有不同的考虑,患者应积极参与选择适合他们的产品。与口服雌激素的风险担忧相反,阴道雌激素的风险特征较低。在使用的禁忌方面,阴道雌激素的绝对禁忌相对较少。全面了解阴道雌激素的安全性、有效性和正确使用方法对治疗绝经后女性的泌尿科医生至关重要。