Staals Eric Lodewijk, Sambri Andrea, Campanacci Domenico Andrea, Muratori Francesco, Leithner Andreas, Gilg Magdalena Maria, Gortzak Yair, Van De Sande Michiel, Dierselhuis Edwin, Mascard Eric, Windhager Reinhard, Funovics Philipp, Schinhan Martina, Vyrva Oleg, Sys Gwen, Bolshakov Nikolay, Aston Will, Gikas Panagiotas, Schubert Thomas, Jeys Lee, Abudu Adesegun, Manfrini Marco, Donati Davide Maria
Orthopedic Surgery, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Orthopedic Surgery, AOSP Sant'Orsola-Malpighi, Bologna, Italy.
J Surg Oncol. 2020 Sep;122(4):760-765. doi: 10.1002/jso.26060. Epub 2020 Jun 7.
Expandable distal femur prostheses have become more popular over the last decades, but scientific data is limited.
A retrospective study was performed, including cases treated between 1986 and 2019 in 15 European referral centers for bone sarcomas.
A total of 299 cases were included. Average follow-up was 80 months (range, 8-287 months). Mean patient age was 10 years. Most (80%) of the implants were noninvasive growers and a fixed hinge knee was used more often (64%) than a rotating hinge. Most prosthetic designs showed good (>80%) implant survival at 10 years, but repeat surgery was required for 63% of the patients. The most frequent reason for revision procedure was the completion of lengthening potential. Noninvasive expandable implants showed less risk of infection compared to invasive growers (11.8% vs 22.9% at 10 years). No difference in aseptic loosening was found between cemented and uncemented stems.
This study shows the increasing popularity of expandable distal femur prostheses, with overall good results for function and implant survival. However, repeat surgery is frequently required, especially in patients under the age of 10 years old. Infection is less frequent in noninvasive growers compared to implants that require invasive lengthening procedures.
在过去几十年中,可延长型股骨远端假体越来越受欢迎,但相关科学数据有限。
进行了一项回顾性研究,纳入了1986年至2019年期间在15个欧洲骨肉瘤转诊中心接受治疗的病例。
共纳入299例病例。平均随访时间为80个月(范围8 - 287个月)。患者平均年龄为10岁。大多数(80%)植入物为非侵入性生长型,且固定铰链膝关节的使用频率(64%)高于旋转铰链。大多数假体设计在10年时显示出良好(>80%)的植入物生存率,但63%的患者需要再次手术。翻修手术最常见的原因是延长潜力耗尽。与侵入性生长型植入物相比,非侵入性可延长植入物在10年时感染风险更低(11.8%对22.9%)。骨水泥型和非骨水泥型柄在无菌性松动方面未发现差异。
本研究表明可延长型股骨远端假体越来越受欢迎,功能和植入物生存率总体良好。然而,经常需要再次手术,尤其是10岁以下的患者。与需要侵入性延长手术的植入物相比,非侵入性生长型植入物感染频率更低。