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抗 NMDAR 脑炎:一种识别疾病和管理精神症状的多学科方法。

Anti-NMDAR Encephalitis: A Multidisciplinary Approach to Identification of the Disorder and Management of Psychiatric Symptoms.

机构信息

Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD.

Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD.

出版信息

Psychosomatics. 2020 Sep-Oct;61(5):456-466. doi: 10.1016/j.psym.2020.04.017. Epub 2020 Apr 29.

Abstract

BACKGROUND

The novelty of anti-NMDA receptor encephalitis, for which somatic treatments have only recently been developed, has led to a lack of information on assessment and treatment of its variable behavioral manifestations.

METHOD

In this article, we discuss 4 challenging cases of anti-NMDAR encephalitis, focusing on the importance of a multidisciplinary approach to identification and management of the disorder and the necessity of close collaboration in the acute hospital setting for management of the behavioral symptoms.

CONCLUSION

The cases we discuss highlight some of the medication and nonpharmacologic treatment strategies that may facilitate management of psychiatric symptoms, both while the medical workup is ongoing and after the diagnosis has been confirmed.

摘要

背景

抗 NMDA 受体脑炎是一种新出现的疾病,最近才开发出针对其的躯体治疗方法,因此对于其各种不同的行为表现的评估和治疗方法,信息相对匮乏。

方法

本文讨论了 4 例具有挑战性的抗 NMDA 受体脑炎病例,重点介绍了多学科方法在识别和管理这种疾病方面的重要性,以及在急性医院环境中密切合作管理行为症状的必要性。

结论

我们所讨论的病例突出了一些药物和非药物治疗策略,这些策略可能有助于管理精神症状,无论是在进行医学检查的过程中,还是在确诊之后。

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