Lei Siyu, Mulmi Shrestha Sachin, Shi Ruihua
School of Medicine, Southeast University, Nanjing, China.
Department of Gastroenterology, Zhongda Hospital Affiliated to Southeast University, No. 87 Ding Jia Qiao, Nanjing, Jiangsu 210009, China.
Gastroenterol Res Pract. 2020 May 14;2020:4152453. doi: 10.1155/2020/4152453. eCollection 2020.
Esophageal squamous cell carcinoma comprises the majority of esophageal carcinoma in the Eastern Asia. The need of early detection of precancerous neoplastic lesions and cancer has been necessitated due to the probability of progression to the advanced stage and its poor prognosis. In recent times, many endoscopic modalities have come into practice for early detection and treatment. Endoscopic radiofrequency ablation (RFA) has been recommended as an efficient therapy in treating the dysplastic mucosa in Barrett's esophagus (BE). Its potential in reversing neoplastic lesions in squamous epithelium has been gradually explored. This article is aimed at reviewing the current evidence regarding the use of RFA on esophageal squamous cell neoplasia.
食管鳞状细胞癌在东亚地区占食管癌的大多数。由于癌前肿瘤性病变进展至晚期的可能性及其预后较差，因此有必要对其进行早期检测。近年来，许多内镜检查方法已应用于早期检测和治疗。内镜下射频消融术（RFA）已被推荐为治疗巴雷特食管（BE）发育异常黏膜的有效疗法。其在逆转鳞状上皮肿瘤性病变方面的潜力也在逐步探索。本文旨在综述目前关于RFA用于食管鳞状细胞肿瘤的证据。
