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灌注骨水泥螺钉在骨质疏松性腰椎退变性疾病中的应用

[Application of perfusion bone cement screw in lumbar degenerative disease with osteoporosis].

作者信息

Qu Yi, Yu Xing, Wang Feng-Xian, Yang Ji-Zhou, Yang Yong-Dong, Zhao Ding-Yan, Wang He-Jun, Chen Si-Xue

机构信息

Department of Orthopaedics, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100700, China;

出版信息

Zhongguo Gu Shang. 2019 Oct 25;32(10):928-932. doi: 10.3969/j.issn.1003-0034.2019.10.011.

Abstract

OBJECTIVE

To observe the early clinical effect of perfusion bone cement screw for lumbar degenerative diseases with osteoporosis.

METHODS

The clinical data of 28 patients with lumbar degenerative diseases combined with moderate to severe osteoporosis treated by posterior lateral graft fusion with perfusion of bone cement screws from June 2015 to June 2017 were retrospectively analyzed. There were 9 males and 19 females, aged from 55 to 86 years old with an average of 76 years. Anteroposterior, oblique, and dynamic radiography were performed before operation, and the diagnosis was confirmed by CT, MRI and dual energy X-ray absorptionmetry(DXA). All the patients had moderate to severe lumbar spinal stenosis, including 16 cases with degenerative scoliosis, 12 cases with degenerative lumbar spondylolisthesis, and 16 cases with lumbar disc herniation. According to Jikei grade of osteoporosis, 9 cases were grade II and 19 cases were grade III. Visual analogue scale (VAS) and Japanese Orthopaedic Association (JOA) score were used to assess the improvement of lumbar leg pain, and neurological function. Imaging data were used to observe the circumstance of pedicle loosening, prolapse, breakage and bone cement leakage, and comprehensively evaluate the fusion.

RESULTS

The hospital stay was from 10 to 14 days with an average of 12 days; the operative time was 100 to 150 min with an average of 120 min;the blood loss was 200 to 600 ml with an average of 350 ml (for operations more than 3 vertebral segments, blood filtration recovery was intraoperatively used);the postoperative drainage volume was 150 to 600 ml with an average of 300 ml, no allogeneic blood was used in all the patients. Bone cement of 2 to 3 ml were injected into each vertebral body, and bone cement leakage occurred in 2 cases during injection, both of which were paravertebral vessel leakage, and there was no evidence of intravertebral leakage. The injection of bone cement was terminated in a timely manner without serious complications such as nerve injury, bone cement toxicity, and vascular embolization and pulmonary embolism. According to the fusion criteria by X-ray, 18 cases achieved strong bone fusion, and 10 cases were inaccurate fusion, but no pseudarthrosis occurred in the fusion segment. No screw loosening, prolapse or fracture were found, and postoperative VAS, JOA scores were significantly improved.

CONCLUSIONS

Perfusion bone cement screw technique can obtain satisfactory effect in treating lumbar degenerative diseases with osteoporosis.

摘要

目的

观察灌注骨水泥螺钉治疗合并骨质疏松的腰椎退变性疾病的早期临床效果。

方法

回顾性分析2015年6月至2017年6月采用后路外侧植骨融合并灌注骨水泥螺钉治疗的28例合并中重度骨质疏松的腰椎退变性疾病患者的临床资料。其中男性9例,女性19例,年龄55至86岁,平均76岁。术前进行正侧位、斜位及动力位X线检查,并通过CT、MRI及双能X线吸收法(DXA)确诊。所有患者均有中重度腰椎管狭窄,其中退行性脊柱侧凸16例,退行性腰椎滑脱12例,腰椎间盘突出症16例。根据日本骨科学会骨质疏松分级,Ⅱ级9例,Ⅲ级19例。采用视觉模拟评分法(VAS)和日本骨科学会(JOA)评分评估腰腿痛及神经功能的改善情况。通过影像学资料观察椎弓根松动、滑脱、断裂及骨水泥渗漏情况,并综合评估融合情况。

结果

住院时间10至14天,平均12天;手术时间100至150分钟,平均120分钟;出血量200至600毫升,平均350毫升(手术超过3个椎体节段时术中采用血液滤过回收);术后引流量150至600毫升,平均300毫升,所有患者均未使用异体血。每个椎体注入骨水泥2至3毫升,注射过程中2例发生骨水泥渗漏,均为椎旁血管渗漏,无椎体内渗漏证据。及时终止骨水泥注射,未出现神经损伤、骨水泥毒性、血管栓塞及肺栓塞等严重并发症。根据X线融合标准,18例达到坚强骨融合,10例融合不准确,但融合节段未发生假关节形成。未发现螺钉松动、滑脱或断裂,术后VAS、JOA评分显著改善。

结论

灌注骨水泥螺钉技术治疗合并骨质疏松的腰椎退变性疾病可获得满意效果。

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