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住院患者的药学服务。(新冠疫情危机的管理。药学服务面临的新挑战)

Pharmaceutical care in hospitalized patients. (Management of the COVID-19 pandemic crisis. A new challenge for pharmacy services).

作者信息

Sevilla-Sánchez Daniel, Tuset-Creus Montse

机构信息

Servicio de Farmacia, Hospital Universitari de Vic (Consorci Hospitalari de Vic), Hospital Universitari de la Santa Creu de Vic, C3RG (Central Catalonia Chronicity Research Group), Universitat de Vic/Universitat Central de Catalunya, Vic. España.

Servicio de Farmacia, Hospital Clínic, Barcelona. España.

出版信息

Farm Hosp. 2020 Jun 12;44(7):28-31. doi: 10.7399/fh.11513.

Abstract

During the pandemic caused by the SARS-CoV-2 virus, pharmacy services have  had to adapt their service portfolio, and yet ensure efficient, equitable and  quality pharmaceutical care. Given the limited scientific evidence available, most drugs have been used off-label or in the context of clinical trials, which should be the preferred option in order to create new evidence. Among kind different  situations we have faced are the increase in workload, the expansion of  coverage to new wards and ICUs and shortages, which have caused the use of  alternative drugs and even other routes of administration. Given that covid-19  affects elderly population with greater severity and many of them are  polymedicated, great effort have been focused on monitoring interactions, both  pharmacokinetic and pharmacodynamic (specially prolongation of the QT  interval), monitoring correct concentrations of electrolytes, nutritional support,  adaptation of chemotherapy treatment protocols and anticoagulant  management, among others. The use of personal protective equipment added  difficulty for nursing work and some measures had been taken to minimize the  number of entries into the rooms. Eventually, team's split to guarantee care, the challenge of teleworking, remote validation, telemedicine and telepharmacy for  communication between professionals and patients, as well as training in this pandemic situation have been a challenge for our profession. These  difficulties have risen up new learning opportunities we hope will be useful to us  in the event we have to face similar situations in the future.

摘要

在由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)病毒引起的大流行期间,药房服务不得不调整其服务组合,但仍要确保提供高效、公平和优质的药学服务。鉴于现有科学证据有限,大多数药物都是在标签外使用或在临床试验背景下使用,而临床试验应该是创造新证据的首选方案。我们面临的不同情况包括工作量增加、覆盖范围扩大到新的病房和重症监护病房以及药品短缺,这些情况导致了替代药物的使用甚至其他给药途径。鉴于2019冠状病毒病对老年人群的影响更为严重,而且他们中的许多人同时服用多种药物,因此我们付出了巨大努力,重点关注药物相互作用的监测,包括药代动力学和药效学方面(特别是QT间期延长)、监测电解质的正确浓度、营养支持、调整化疗治疗方案和抗凝管理等。个人防护设备的使用给护理工作增加了难度,我们已经采取了一些措施来尽量减少进入病房的次数。最终,团队进行了拆分以确保护理工作,远程办公、远程验证、远程医疗和远程药房在专业人员与患者之间进行沟通所带来的挑战,以及在这种大流行情况下的培训,都对我们的职业构成了挑战。这些困难带来了新的学习机会,我们希望在未来我们不得不面对类似情况时,这些机会将对我们有所帮助。

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