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腹腔镜 Heller 肌切开术和 Roux-en-Y 胃旁路术治疗贲门失弛缓症合并病态肥胖:短系列患者的结果。

Laparoscopic Heller Myotomy and Roux-en-Y Gastric Bypass as Treatment for Patients with Achalasia and Morbid Obesity: Outcomes in a Short Series of Patients.

机构信息

Department of Surgery, Hospital de Gastroenterología "Dr. Carlos Bonorino Udaondo," Ciudad Autónoma de Buenos Aires, Argentina.

出版信息

J Laparoendosc Adv Surg Tech A. 2021 Jan;31(1):29-35. doi: 10.1089/lap.2020.0331. Epub 2020 Jun 17.

DOI:10.1089/lap.2020.0331
PMID:32552364
Abstract

The association between morbid obesity and esophageal achalasia is very infrequent. However, over the last decade, these cases started to increase because of the disturbing rise of morbid obesity worldwide. Heller myotomy (HM) and laparoscopic fundoplication represent the best treatment option for esophageal achalasia. However, in morbidly obese patients with achalasia, the best treatment option is not established. We present laparoscopic HM and Roux-en-Y gastric bypass (RYGB) as an alternative treatment for morbidly obese patients with achalasia. We analyzed the course of patients with achalasia and morbid obesity in our institution undergoing a laparoscopic HM and RYGB, with at least 1 year of follow-up. Symptoms questionnaire, body mass index (BMI), and minuted esophagogram before and after treatment were performed in all patients. Seven patients underwent laparoscopic HM and RYGB. All patients had dysphagia. The mean BMI before the onset of symptoms was 42 kg/m (range 40 to 50). In 5 patients, preoperative contrast esophagram showed mild or marked dilated esophagus, and in 2, one esophageal curve and severe dilation. Manometry confirmed the diagnosis. At a mean follow-up of 38 months (range 14-69), all patients reported a marked improvement in dysphagia, with median overall satisfaction rating of 10 (range 9-10), and no symptom of gastroesophageal reflux disease (GERD). The mean percentage excess weight loss (%EWL) was 77.1% (range 70.1-98.1) and the mean BMI was 25.7 kg/m (range 23-31). HM and RYGB are an excellent treatment for morbidly obese patients with achalasia. All patients reported a marked improvement of their dysphagia and no symptoms of GERD. The %EWL and BMI descent was very good and maintained through time, showing also an excellent control for morbid obesity.

摘要

肥胖合并贲门失弛缓症非常少见。然而,在过去的十年中,由于全球肥胖症的发病率不断上升,这种情况开始增多。Heller 肌切开术(HM)和腹腔镜胃底折叠术是贲门失弛缓症的最佳治疗选择。然而,对于肥胖合并贲门失弛缓症的患者,最佳治疗选择尚未确定。我们提出腹腔镜 HM 和 Roux-en-Y 胃旁路术(RYGB)作为肥胖合并贲门失弛缓症患者的替代治疗方法。我们分析了在我们机构接受腹腔镜 HM 和 RYGB 治疗的贲门失弛缓症和肥胖症患者的病程,这些患者的随访时间至少为 1 年。所有患者均进行症状问卷、体重指数(BMI)和治疗前后的分钟食管造影检查。7 例患者接受了腹腔镜 HM 和 RYGB。所有患者均有吞咽困难。症状出现前的平均 BMI 为 42kg/m²(范围 40 至 50)。在 5 例患者中,术前对比食管造影显示轻度或明显扩张的食管,在 2 例中,一条食管曲线和严重扩张。测压法证实了诊断。在平均 38 个月(范围 14-69)的随访中,所有患者均报告吞咽困难明显改善,总体满意度评分为 10 分(范围 9-10),无胃食管反流病(GERD)症状。平均超重减轻百分比(%EWL)为 77.1%(范围 70.1-98.1),平均 BMI 为 25.7kg/m²(范围 23-31)。HM 和 RYGB 是肥胖合并贲门失弛缓症患者的极佳治疗方法。所有患者均报告吞咽困难明显改善,无 GERD 症状。%EWL 和 BMI 的下降非常好,并随时间保持稳定,对肥胖症也有极好的控制。

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