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创伤后异位骨化导致的肘部僵硬的治疗方法。

Treatment methods for post-traumatic elbow stiffness caused by heterotopic ossification.

机构信息

Department of Orthopaedic Surgery, Columbia University Medical Center/Presbyterian Hospital, New York, NY, USA.

Department of Orthopaedic Surgery, Columbia University Medical Center/Presbyterian Hospital, New York, NY, USA.

出版信息

J Shoulder Elbow Surg. 2020 Jul;29(7):1380-1386. doi: 10.1016/j.jse.2020.02.026.

Abstract

HYPOTHESIS

Heterotopic ossification (HO) is a common complication of surgically treated elbow fractures that can inhibit range of motion and impair quality of life. Although there are many treatment methods for HO, there is a lack of consensus as to the best option. We hypothesized that contracture release combined with Botox injection would lead to improved functional outcome scores when compared with current treatment methods.

METHODS

A retrospective review was conducted of patients who presented to a single surgeon with HO secondary to elbow fracture between 2005 and 2018. A total of 59 patients were identified who met inclusion criteria. Data were classified into 3 groups: contracture release (control - CR), Botox injection with CR (Botox + CR), and radiation therapy with CR (CR + RT). Range of motion measurements were obtained, including flexion, extension, pronation, and supination.

RESULTS

A total of 30 patients (30 of 59, 50.8%) received CR, 6 (6 of 59, 9.2%) were treated with CR + RT, and 23 (23 of 59, 40.0%) had CR + Botox. There was a significant difference between pre- and postoperative arc of motion for both CR + RT (P < .01) and CR + Botox (P < .01). In addition, there was a significant difference in pre- and postoperative extension for patients who received intraoperative Botox injections (P < .05). There was no significant difference between pre- and postoperative motion nor extension in the CR group.

CONCLUSION

Intraoperative Botox injection with CR is an effective method in the treatment of post-traumatic elbow stiffness caused by HO.

摘要

假设

异位骨化(HO)是肘部骨折手术后的常见并发症,会限制关节活动度并降低生活质量。尽管有许多治疗 HO 的方法,但对于最佳治疗方案仍存在争议。我们假设与目前的治疗方法相比,挛缩松解联合肉毒毒素注射可改善功能预后评分。

方法

对 2005 年至 2018 年间因肘部骨折而发生 HO 并由一位外科医生治疗的患者进行了回顾性研究。共确定了 59 名符合纳入标准的患者。将数据分为 3 组:挛缩松解(对照组-CR)、CR 联合肉毒毒素注射(Botox+CR)和 CR 联合放射治疗(CR+RT)。获得了包括屈曲、伸展、旋前和旋后在内的关节活动度测量值。

结果

共有 30 名患者(59 名中的 30 名,50.8%)接受了 CR,6 名(59 名中的 6 名,9.2%)接受了 CR+RT,23 名(59 名中的 23 名,40.0%)接受了 CR+Botox。CR+RT(P<0.01)和 CR+Botox(P<0.01)的术前和术后运动弧均有显著差异。此外,接受术中肉毒毒素注射的患者的术后伸展度也有显著差异(P<0.05)。CR 组的术前和术后运动度以及伸展度均无显著差异。

结论

CR 联合术中肉毒毒素注射是治疗由 HO 引起的创伤后肘部僵硬的有效方法。

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