Jwa Eun-Kyoung, Choi Dong Lak, Kim Joo Dong
Division of Hepatobiliary Pancreas Surgery and Abdominal Organ Transplantation, Daegu Catholic University College of Medicine, Daegu, Korea.
Division of Hepatobiliary Pancreas Surgery and Abdominal Organ Transplantation, Daegu Catholic University College of Medicine, Daegu, Korea.
Transplant Proc. 2020 Jul-Aug;52(6):1791-1793. doi: 10.1016/j.transproceed.2020.02.142. Epub 2020 Jun 20.
Living donor liver transplantation (LDLT) from donors with complex portal vein anomalies has been considered a challenging procedure because vasculobiliary variations of the donor's liver may lead to significant increases in donor and recipient complications. The use of donors with anatomic variations may be considered under the accurate preoperative planning if a more suitable donor is not available. We report a successful dual LDLT for 2 donors with portal vein anomaly to overcome the small-for-size graft syndrome and secure donor safety. A 62-year-old man was referred to our institution for liver transplant because of hepatitis B-related liver cirrhosis with hepatocellular carcinoma. The only available donors were his son and his daughter-in-law, one with type IV portal venous anatomic variation and the other with type III variation. Neither of the 2 available donors were suitable as a single donor because of the complexity of the portal vein reconstruction and the donor's safety. Therefore, the decision was made to perform LDLT using dual graft, and we planned to harvest the right posterior sector graph from the first donor together with the left lobe graft of the second donor. Donor hepatectomy and recipient total hepatectomy were performed in the usual manner. He has recovered well with normal graft function, and there has been no tumor recurrence after dual LDLT. Dual graft LDLT using right posterior sector and left lobe graft could be undertaken successfully to overcome the small-for-size graft syndrome and secure the safety of donors in cases with the complex portal vein anomalies.
来自门静脉存在复杂异常的供体的活体肝移植(LDLT)被认为是一项具有挑战性的手术,因为供体肝脏的血管胆道变异可能导致供体和受体并发症显著增加。如果没有更合适的供体,在准确的术前规划下可以考虑使用存在解剖变异的供体。我们报告了一例为两名门静脉异常供体成功实施的双供体LDLT,以克服小体积移植物综合征并确保供体安全。一名62岁男性因乙型肝炎相关肝硬化合并肝细胞癌被转诊至我院进行肝移植。仅有的可用供体是他的儿子和儿媳,其中一人存在IV型门静脉解剖变异,另一人存在III型变异。由于门静脉重建的复杂性和供体安全问题,这两名可用供体都不适合作为单供体。因此,决定采用双移植物进行LDLT,我们计划从第一个供体获取右后叶移植物,同时从第二个供体获取左叶移植物。以常规方式进行供体肝切除术和受体全肝切除术。他恢复良好,移植物功能正常,双供体LDLT后未出现肿瘤复发。对于门静脉复杂异常的病例,使用右后叶和左叶移植物的双移植物LDLT可以成功实施,以克服小体积移植物综合征并确保供体安全。