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腹腔镜胃造瘘术后早期与晚期开始肠内喂养方案对小儿患者结局的影响。

Outcomes Associated With Early vs Late Initiation of Exclusive Enteral Feeding Regimens Following Laparoscopic Gastrostomy Tube Placement in the Pediatric Patient.

机构信息

University of Tennessee Health Science Center, Memphis, Tennessee, USA.

Pediatric Gastroenterology, University of Michigan, Ann Arbor, Michigan, USA.

出版信息

Nutr Clin Pract. 2020 Oct;35(5):911-918. doi: 10.1002/ncp.10503. Epub 2020 Jun 24.

Abstract

OBJECTIVES

Despite frequent placement of pediatric laparoscopic gastrostomy tubes (GTs), no rigorous evaluation of initial feeding and advancement regimens exists. Therefore, the aim of this study was to determine whether early enteral feeding after GT placement is associated with increased symptoms, procedural complications, or length of stay (LOS).

METHODS

In this retrospective cohort study, the records of all patients at a tertiary care pediatric hospital who had gastrostomy placement were reviewed. Only patients fed exclusively via gastrostomy were included. Feeding was monitored starting with the first postoperative feed and subsequently in 24-hour increments. Adverse events were recorded based on clinical documentation.

RESULTS

A total of 480 patients met inclusion criteria. Patients who started feeds between 24 and 36 hours had a shorter LOS compared with those who started at 36-48 hours (P = .0072) or >48 hours (P < .0001). Patients requiring ≥60 hours to reach goal feeds had significantly longer LOS than the other groups. There was no difference in the distribution of the LOS based on percentage of goal feeds initiated. Patients who required ≥60 hours to attain goal feeds had the most feeding complications.

CONCLUSIONS

More aggressive feeding advancement and earlier initiation of feeds were associated with decreased LOS without an associated increase in adverse clinical events.

摘要

目的

尽管小儿腹腔镜胃造口术(GT)经常进行,但目前尚缺乏严格评估初始喂养和推进方案的研究。因此,本研究旨在确定 GT 放置后早期肠内喂养是否与症状、程序并发症或住院时间(LOS)增加有关。

方法

在这项回顾性队列研究中,对一家三级儿科医院所有接受胃造口术的患者的记录进行了回顾。仅纳入通过胃造口术进行完全喂养的患者。从术后第一次喂养开始,并随后以 24 小时为增量进行喂养监测。根据临床记录记录不良事件。

结果

共有 480 名患者符合纳入标准。与在 36-48 小时(P=.0072)或>48 小时(P<.0001)开始喂养的患者相比,在 24-36 小时开始喂养的患者 LOS 更短。需要≥60 小时才能达到目标喂养量的患者 LOS 明显长于其他组。基于开始的目标喂养量的百分比,LOS 的分布没有差异。需要≥60 小时才能达到目标喂养量的患者发生喂养并发症的比例最高。

结论

更积极的喂养推进和更早的喂养开始与 LOS 减少相关,而没有相关的不良临床事件增加。

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