Shah Arya, Magaña Setty M, E Youssef Paul
Brigham and Women's Hospital, Boston, MA, USA.
Division of Child and Adolescent Neurology, Department of Neurology, Mayo Clinic, Rochester, MN, USA.
Child Neurol Open. 2020 Jun 12;7:2329048X20932714. doi: 10.1177/2329048X20932714. eCollection 2020 Jan-Dec.
Alice in Wonderland syndrome is a disorienting perceptual disorder characterized by discrete episodes of bizarre visual illusions and spatial distortions which has been associated with numerous neurologic and psychiatric conditions. Little is known regarding the electrophysiologic correlates of the visual symptoms described in this syndrome. The authors report the unique case of an 8-year-old boy presenting with visual distortions consistent with Alice in Wonderland syndrome, and an electroencephalogram demonstrating bilateral temporo-occipital slowing which correlated with symptoms of micropsia, teleopsia, and dysmorphopsia. Identification of this clinical syndrome and its electroclinical features are important for establishing a proper diagnosis and subsequent reassurance or appropriate treatment directed toward the underlying etiology.
爱丽丝梦游仙境综合征是一种令人迷失方向的感知障碍，其特征为间歇性出现离奇的视觉幻觉和空间扭曲，与多种神经和精神疾病有关。对于该综合征所描述的视觉症状的电生理相关性，人们知之甚少。作者报告了一例独特病例，一名8岁男孩出现与爱丽丝梦游仙境综合征相符的视觉扭曲，脑电图显示双侧颞枕部减慢，这与视物显小症、视物显大症和视物变形症的症状相关。识别这种临床综合征及其电临床特征对于确立正确诊断以及随后针对潜在病因给予安心治疗或适当治疗很重要。
