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尼洛替尼致儿童毛囊角化病样疹。

Keratosis pilaris-like eruption secondary to nilotinib in a child.

机构信息

Department of Dermatology, University Hospital of Pontevedra, Pontevedra (Galicia), Spain.

Department of Dermatology, University Hospital La Paz, Madrid, Spain.

出版信息

Pediatr Dermatol. 2020 Sep;37(5):968-969. doi: 10.1111/pde.14267. Epub 2020 Jun 29.

Abstract

Nilotinib is a new multitargeted tyrosine kinase inhibitor, which is used to treat chronic myelogenous leukemia when intolerance or recurrence to imatinib occurs. We report the case of a 14-year-old patient being treated with nilotinib who developed a keratosis pilaris-like eruption. This cutaneous adverse effect is a rare but increasingly reported side effect of this therapy.

摘要

尼洛替尼是一种新型的多靶点酪氨酸激酶抑制剂,用于治疗对伊马替尼不耐受或复发的慢性髓性白血病。我们报告了一例使用尼洛替尼治疗的 14 岁患者,该患者出现了类似于毛发角化病的皮疹。这种皮肤不良反应是该治疗方法的一种罕见但越来越多被报道的副作用。

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