中枢神经系统病变的流行病学和组织学特征：黎巴嫩一家三级中心 20 年的经验。
Epidemiologic and histologic characteristics of CNS lesions: a 20-year experience of a tertiary center in Lebanon.
机构信息
Department of Hematology-Oncology, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.
Department of Pathology, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.
出版信息
CNS Oncol. 2020 Jun;9(2):CNS55. doi: 10.2217/cns-2020-0001. Epub 2020 Jun 30.
Report the epidemiologic and histologic characteristics of CNS lesions in the Lebanese population. We conducted a retrospective study evaluating 2025 CNS lesions diagnosed between 1998 and 2017 in the pathology laboratory of a Lebanese tertiary center. 52.2% of patients were men with a median age of 50 years. The most frequent symptoms were epilepsy (22.5%), headache (20.6%) and motor impairment (19.9%). 90.7% of tumors were primary. Lung (35.6%) and breast (16.5%) were the most frequent primaries of metastases. 46.2% of primary CNS tumors were glial, predominantly astrocytic (56.4%), and (42.5%) were nonglial, predominantly meningeal tumors (58%). Compared with Western literature, the Lebanese population is characterized by a younger age of onset of brain tumors, a lower rate of meningiomas and a higher rate of gliomas.
报告黎巴嫩人群中枢神经系统病变的流行病学和组织学特征。我们进行了一项回顾性研究，评估了 1998 年至 2017 年间在黎巴嫩一家三级中心的病理学实验室诊断的 2025 例中枢神经系统病变。52.2%的患者为男性，中位年龄为 50 岁。最常见的症状是癫痫（22.5%）、头痛（20.6%）和运动障碍（19.9%）。90.7%的肿瘤为原发性。肺（35.6%）和乳腺（16.5%）是转移瘤最常见的原发部位。46.2%的原发性中枢神经系统肿瘤为神经胶质，主要为星形细胞瘤（56.4%），42.5%为非神经胶质，主要为脑膜瘤（58%）。与西方文献相比，黎巴嫩人群的特点是脑瘤发病年龄更年轻，脑膜瘤发病率更低，神经胶质瘤发病率更高。
Zotero 插件