Department of Pathology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Clin Nucl Med. 2020 Nov;45(11):890-891. doi: 10.1097/RLU.0000000000003158.
Localized malignant mesothelioma is rare. The prognosis is generally more favorable for this condition than for diffuse malignant mesothelioma. An elderly woman recently complained of abdominal pain, fever, and weight loss. She had no history of asbestos exposure. Her serum CEA level was elevated. Plain CT revealed a mass under the left diaphragm, with liquefaction and necrosis. A contrast-enhanced scan showed circular enhancement of the mass. A subsequent biopsy of the mass revealed a poorly differentiated carcinoma. PET/CT showed a significant FDG-avid subphrenic mass without any indications of metastasis. Postoperative pathological and immunohistochemical examination confirmed a case of malignant mesothelioma.
局限性恶性间皮瘤较为罕见。与弥漫性恶性间皮瘤相比,其预后通常更为有利。一位老年女性最近主诉腹痛、发热和体重减轻。她没有石棉暴露史。其血清 CEA 水平升高。腹部 CT 平扫显示左膈肌下有一肿块,伴液化和坏死。增强扫描显示肿块呈环形强化。随后对肿块进行活检,结果显示为低分化癌。PET/CT 显示膈下有明显 FDG 摄取的肿块,但无转移迹象。术后病理和免疫组织化学检查证实为恶性间皮瘤。