Wei Xiao-Xia, He Yan-Mei, Jiang Wei, Li Lei
Department of Pathology, West China Second University Hospital, Sichuan University/Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Chengdu 610041, Sichuan Province, China.
World J Clin Cases. 2020 Jun 26;8(12):2623-2628. doi: 10.12998/wjcc.v8.i12.2623.
Ovarian endometrioid carcinoma resembling sex cord-stromal tumor (ECSCSs) is rare.
We present a rare case of primary ECSCSs in the left ovary. A 39-year-old female patient had persistent dull pain in the lower abdomen for more than 1 mo, and she was initially diagnosed with pelvic inflammatory disease at a hospital. The patient received transabdominal hysterectomy, bilateral salpingo-oophorectomy, and pelvic and para-aortic lymph node dissection at our hospital and finally diagnosed with ECSCSs. After the operation, the patient received eight courses of cisplatinum + etoposide + bleomycin chemotherapy treatment and no evidence of tumor recurrence or metastasis was found in a 2-year follow-up period.
Ovarian endometrioid carcinoma is similar to the ovary sex cord-stromal tumor, especially when the cord-like structure is obvious. The clinical diagnosis for this tumor is difficult before surgery and pathology examination. The necessary immunohistochemical markers are of positive significance for assisting diagnosis and differential diagnosis.
卵巢子宫内膜样癌酷似性索间质肿瘤(ECSCSs)的情况较为罕见。
我们报告1例罕见的左侧卵巢原发性ECSCSs。1例39岁女性患者下腹部持续性隐痛1个多月,最初在某医院被诊断为盆腔炎。该患者在我院接受了经腹子宫切除术、双侧输卵管卵巢切除术及盆腔和腹主动脉旁淋巴结清扫术,最终诊断为ECSCSs。术后,患者接受了8个疗程的顺铂+依托泊苷+博来霉素化疗,在2年随访期内未发现肿瘤复发或转移迹象。
卵巢子宫内膜样癌与卵巢性索间质肿瘤相似,尤其是条索状结构明显时。术前及病理检查前,该肿瘤的临床诊断困难。必要的免疫组化标志物对辅助诊断及鉴别诊断具有重要意义。