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荷兰的死后组织捐献:一种全国性的方法。

Post mortem tissue donation in the Netherlands: a nationwide approach.

机构信息

Dutch Transplant Foundation, Leiden, The Netherlands.

Transplant Surgery, Leiden University Medical Center, Leiden, The Netherlands.

出版信息

Cell Tissue Bank. 2021 Jun;22(2):185-190. doi: 10.1007/s10561-020-09846-z. Epub 2020 Jul 1.

DOI:10.1007/s10561-020-09846-z
PMID:32607682
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7326619/
Abstract

In this article we describe the organization of post mortem tissue donation in the Netherlands, the average number of tissue donors procured during the years 2015-2019 and the main challenges we face to improve this number. Licensed by the Dutch Ministry of Health, the Dutch Transplant Foundation (NTS) plays a central role in the organization of tissue donation. The NTS works closely with the Dutch hospitals, two tissue banks and a procurement organization. Potential tissue donors are reported to the NTS 24/7. After consulting the Donor Register and relatives give consent for donation, donors are subject to a thorough medical evaluation. If no medical contraindication is mentioned, the donor is approved for tissue donation. Each year, tissues of an average of 1918 donors (112.1 donors Per Million Population) are procured. After procurement of tissues, donor blood and tissues are tested on virology and quality respectively. Based on the test results and the assessment of potential disease transmission, tissues can either be released for transplantation or discarded. In conclusion, the Netherlands has developed a uniform, nationwide approach for safe and efficient post mortem tissue donation in which the NTS plays a central role. In the past 5 years, tissues from a considerable number of donors are procured. The NTS will continue to work together with their partners, by stimulating donor recognition, registration of the donor will, relatives' informed consent and by extending donor selection criteria, for an even more efficient way to help patients on the waiting list for a transplantation.

摘要

本文描述了荷兰的尸检组织捐献组织情况、2015-2019 年期间获取的组织捐献者的平均数量,以及为提高这一数字我们所面临的主要挑战。荷兰卫生部授权,荷兰移植基金会(NTS)在组织捐献方面发挥着核心作用。NTS 与荷兰医院、两家组织库和一家采购组织密切合作。潜在的组织捐献者 24/7 向 NTS 报告。在咨询了捐献者登记册并获得亲属同意捐献后,对捐献者进行彻底的医学评估。如果没有提到医学禁忌症,捐献者将被批准进行组织捐献。平均每年获取 1918 名捐献者(每百万人口 112.1 名捐献者)的组织。组织采集后,对供者血液和组织分别进行病毒学和质量检测。根据检测结果和潜在疾病传播的评估,组织可以放行用于移植或丢弃。总之,荷兰已经开发出一种统一的、全国性的安全有效的尸检组织捐献方法,NTS 在其中发挥了核心作用。在过去的 5 年中,已经获取了相当数量的捐献者的组织。NTS 将继续与合作伙伴合作,通过鼓励识别捐献者、登记捐献意愿、获得亲属的知情同意,以及扩大捐献者选择标准,以更有效地帮助等待移植的患者。

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本文引用的文献

1
Improving recognition of potential tissue donors: a quality improvement project by a hospitalist in training in The Hague, The Netherlands.提高对潜在组织捐赠者的识别率:荷兰海牙一名住院医师培训学员开展的质量改进项目。
Cell Tissue Bank. 2018 Dec;19(4):777-782. doi: 10.1007/s10561-018-9733-y. Epub 2018 Nov 16.
2
Are all tissue donors recognised? A cohort study in three Dutch hospitals.所有组织捐赠者都能被识别出来吗?一项在荷兰三家医院开展的队列研究。
Cell Tissue Bank. 2014 Sep;15(3):483-90. doi: 10.1007/s10561-013-9418-5. Epub 2013 Dec 20.
3
Medical students' knowledge and attitudes toward organ donation: results of a Dutch survey.医学生对器官捐赠的知识与态度:一项荷兰调查的结果
Transplant Proc. 2013 Jul-Aug;45(6):2093-7. doi: 10.1016/j.transproceed.2013.02.135.
4
Higher refusal rates for organ donation among older potential donors in the Netherlands: impact of the donor register and relatives.荷兰老年潜在器官捐献者的器官捐献拒绝率较高:与捐献登记和亲属有关。
Transplantation. 2010 Sep 27;90(6):677-82. doi: 10.1097/TP.0b013e3181eb40fe.