Stanford University.
Am J Intellect Dev Disabil. 2020 Jul 1;125(4):247-259. doi: 10.1352/1944-7558-125.4.247.
Limited information is available concerning the specificity of the forms and functions of aggressive behavior exhibited by boys with fragile X syndrome (FXS). To investigate these relationships, we conducted indirect functional assessments of aggressive behavior exhibited by 41 adolescent boys with FXS and 59 age and symptom-matched controls with intellectual and developmental disability (IDD) and compared the data between groups. Results showed that boys with FXS were more likely to exhibit specific forms of aggressive behavior (i.e., scratching others and biting others) compared to controls, but the sources of reinforcement identified for aggression were similar across groups. Boys with FXS who were prescribed psychotropic medications were more likely to be older and to exhibit more forms of aggression. The implications for the treatment of aggressive behavior during this critical developmental period in FXS are discussed.
关于脆性 X 综合征（FXS）男孩表现出的攻击行为的形式和功能的特异性，相关信息有限。为了研究这些关系，我们对 41 名患有 FXS 的青少年男孩和 59 名年龄和症状相匹配的伴有智力和发育障碍（IDD）的对照组进行了攻击行为的间接功能评估，并对组间数据进行了比较。结果表明，与对照组相比，患有 FXS 的男孩更有可能表现出特定形式的攻击行为（例如，抓人和咬人），但两组的攻击强化来源相似。服用精神药物的 FXS 男孩更有可能年龄较大，表现出更多的攻击行为。讨论了在 FXS 的这个关键发育时期治疗攻击行为的意义。
