Heikkinen Minna, Kallankari Hanna, Partanen Lea, Korkalainen Noora, Kaukola Tuula, Yliherva Anneli
Faculty of Humanities, Child Language Research Center, University of Oulu, Oulu, Finland.
PEDEGO Research Unit and Medical Research Center Oulu, University of Oulu, Oulu, Finland.
Acta Paediatr. 2021 Feb;110(2):521-527. doi: 10.1111/apa.15456. Epub 2020 Aug 19.
Our aim was to study whether prematurity, associated with prenatal and neonatal risk factors, affects specific literacy skills among school children born at a very low gestational age (VLGA) of <32 weeks.
The study group comprised 76 prospectively followed VLGA children born between November 1998 and November 2002 at Oulu University Hospital, Finland, and 51 term controls. The median gestational age of the VLGA children was 29.0 (24.1-31.9) weeks. All children were examined at a median age of 8.9 (8.0-9.9) years in Oulu between November 2007 and November 2011. Reading fluency, comprehension and spelling skills were evaluated using standardised tests for Finnish-speaking children.
Very low gestational age children had significantly poorer test results in reading comprehension (median 6.9 vs 8.3, P = .014) and spelling (median 35.7 vs 38.0, P = .013) than term children. Furthermore, VLGA children more often performed below the 10th percentile normal values in spelling (P = .012) compared with term controls. Foetal growth restriction was associated with lower scoring in reading fluency (P = .023) and spelling (P = .004) among VLGA children.
Very low gestational age school children performed poorer in reading comprehension and spelling than term children. In addition, poor foetal growth in VLGA children was associated with literacy problems.
我们的目的是研究与产前和新生儿风险因素相关的早产是否会影响孕周小于32周的极低出生体重（VLGA）儿童的特定读写能力。
研究组包括1998年11月至2002年11月在芬兰奥卢大学医院前瞻性随访的76名VLGA儿童，以及51名足月儿作为对照。VLGA儿童的中位孕周为29.0（24.1 - 31.9）周。2007年11月至2011年11月期间，所有儿童在奥卢接受检查，中位年龄为8.9（8.0 - 9.9）岁。使用针对芬兰语儿童的标准化测试评估阅读流畅性、阅读理解和拼写能力。
极低出生体重儿童在阅读理解（中位数6.9对8.3，P = 0.014）和拼写（中位数35.7对38.0，P = 0.013）方面的测试结果明显比足月儿差。此外，与足月儿对照组相比，VLGA儿童在拼写方面更常低于第10百分位正常值（P = 0.012）。胎儿生长受限与VLGA儿童的阅读流畅性得分较低（P = 0.023）和拼写得分较低（P = 0.004）相关。
极低出生体重的学龄儿童在阅读理解和拼写方面比足月儿表现更差。此外，VLGA儿童的胎儿生长不良与读写问题相关。
