Badon Sylvia E, Littman Alyson J, Chan Kwun Chuen Gary, Williams Michelle A, Kirkegaard Helene, Nohr Ellen A, Enquobahrie Daniel A
Department of Epidemiology, University of Washington, Seattle, Washington, USA.
Division of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Womens Health Rep (New Rochelle). 2020 May 12;1(1):123-131. doi: 10.1089/whr.2020.0068. eCollection 2020.
Maternal leisure time physical activity (LTPA) and sedentary time during pregnancy may influence programming of infant growth in a sex-specific manner. Participants ( = 35,212) from the Danish National Birth Cohort reported moderate/vigorous LTPA (hours/week) in early (conception to mean 16 weeks of gestation) and late pregnancy (mean 31 weeks of gestation to delivery) during interviews at 16 weeks of gestation and 6 months postpartum. Participants reported screen time at work and time spent watching television/videos (hours/day) in early pregnancy. Infant weight at 12 months of age was reported by mothers. Weight-for-length was categorized using sex-specific international standards. Participants reported on average 1 hour per week of early pregnancy moderate/vigorous LTPA, 0.5 hour per week of late pregnancy LTPA, and 3 hours per day of early pregnancy sedentary time. Early pregnancy LTPA category was not associated with infant weight ( for trend = 0.62). There were suggested associations of early pregnancy sedentary time above the first quartile with greater odds of infant underweight (odds ratio = 1.15-1.27; for trend = 0.27). Associations were similar in male and female infants. There is no clear relationship between early or late pregnancy LTPA and infant weight at 12 months in our study. Maternal early pregnancy sedentary time may be associated with infant underweight at 12 months.
孕期母亲的休闲时间体力活动(LTPA)和久坐时间可能会以性别特异性的方式影响婴儿生长的编程。来自丹麦国家出生队列的35212名参与者在妊娠16周和产后6个月的访谈中报告了孕早期(受孕至妊娠16周)和孕晚期(妊娠31周平均至分娩)的中度/剧烈LTPA(小时/周)。参与者报告了孕早期工作时的屏幕时间以及看电视/视频的时间(小时/天)。母亲报告了婴儿12个月大时的体重。身长体重根据特定性别的国际标准进行分类。参与者报告孕早期平均每周有1小时的中度/剧烈LTPA,孕晚期每周有0.5小时的LTPA,孕早期每天有3小时的久坐时间。孕早期LTPA类别与婴儿体重无关(趋势检验P=0.62)。有迹象表明,孕早期久坐时间高于第一四分位数与婴儿体重不足的几率增加有关(优势比=1.15-1.27;趋势检验P=0.27)。男婴和女婴的关联相似。在我们的研究中,孕早期或孕晚期的LTPA与12个月大婴儿的体重之间没有明确的关系。母亲孕早期的久坐时间可能与婴儿12个月时体重不足有关。