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孤立性打鼾的诊断和治疗——开放性问题和未来研究领域。

Diagnosis and treatment of isolated snoring-open questions and areas for future research.

机构信息

Department of Otorhinolaryngology/Head and Neck Surgery, University Medical Center Freiburg, Killianstr. 5, 79106, Freiburg, Germany.

Department of Otorhinolaryngology/Head and Neck Surgery, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.

出版信息

Sleep Breath. 2021 Jun;25(2):1011-1017. doi: 10.1007/s11325-020-02138-6. Epub 2020 Jul 4.

Abstract

STUDY OBJECTIVES

Snoring is a common phenomenon which is generated by vibration of soft tissue of the upper airway during sleep. Due to the high incidence of isolated snoring and the substantial burden for the patient and the bed partner, a thorough examination and appropriate therapy are required. Many recommendations for the treatment of isolated snoring are either not evidence-based or are derived from recommendations for the management of obstructive sleep apnea. Therefore, the aim of this study is the identification and description of open questions in the diagnosis and treatment of isolated snoring and the illustration of areas for further research.

METHODS

In the context of the development of the new version of the German guideline "Diagnosis and treatment of isolated snoring in adults," a multidisciplinary team of experts performed a systematic literature search on the relevant medical data and rated the current evidence regarding the key diagnostic and therapeutic measures for snoring.

RESULTS

The systematic literature review identified 2293 articles. As a major inclusion criterion, only studies on primary snoring based on objective sleep medical assessment were selected. After screening and evaluation, 33 full-text articles remained for further analysis. Based on these articles, open questions and areas for future research were identified for this review.

CONCLUSION

Several major gaps in the literature on the diagnosis and treatment of isolated snoring were identified. For the majority of diagnostic and therapeutic measures for snoring, high-level scientific evidence is still lacking.

摘要

研究目的

打鼾是一种常见现象,它是睡眠时上呼吸道软组织振动产生的。由于孤立性打鼾的发病率高,且给患者和床伴带来很大负担,因此需要进行彻底检查和适当治疗。许多孤立性打鼾的治疗建议要么没有循证依据,要么源自阻塞性睡眠呼吸暂停管理的建议。因此,本研究旨在确定和描述孤立性打鼾的诊断和治疗中的开放性问题,并阐明进一步研究的领域。

方法

在制定新的德国“成人孤立性打鼾诊断和治疗指南”版本的过程中,一个多学科专家团队对相关医学数据进行了系统的文献检索,并对打鼾的关键诊断和治疗措施的现有证据进行了评估。

结果

系统文献综述共确定了 2293 篇文章。作为主要纳入标准,仅选择了基于客观睡眠医学评估的原发性打鼾的研究。经过筛选和评估,有 33 篇全文文章被纳入进一步分析。基于这些文章,本综述确定了孤立性打鼾的诊断和治疗中的开放性问题和未来研究领域。

结论

孤立性打鼾的诊断和治疗文献中存在几个重大空白。对于大多数打鼾的诊断和治疗措施,仍缺乏高水平的科学证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/330a/8195801/ecaade9e859b/11325_2020_2138_Fig1_HTML.jpg

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