COVID-19 大流行期间糖尿病心血管风险因素管理中的挑战性问题：当前文献综述。
Challenging Issues in the Management of Cardiovascular Risk Factors in Diabetes During the COVID-19 Pandemic: A Review of Current Literature.
机构信息
Department of Medicine, Case Western Reserve University, University Hospitals Cleveland Medical Center, Cleveland, OH, 44106, USA.
Research Center for Prevention of Cardiovascular Disease, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Tehran, Iran.
出版信息
Adv Ther. 2020 Aug;37(8):3450-3462. doi: 10.1007/s12325-020-01417-8. Epub 2020 Jul 6.
The COVID-19 outbreak was declared a pandemic on March 2020. Many patients with SARS-CoV-2 infection have underlying chronic medical conditions such as diabetes, cardiovascular disease (CVD), and hypertension. Patient-related outcomes are worse if there are associated comorbidities. We do not have enough evidence regarding the most appropriate management of patients with diabetes during COVID-19 infection. Insulin resistance and CVD together increase the inflammatory state of the body, which can contribute to and perhaps mediate the increase of COVID-19 severity. Hence, in addition to management of dysglycemia, other CVD risk factors should be targeted. We explore the possible pathophysiologic links between diabetes and COVID-19 and discuss various options to treat dysglycemia, hypertension, and dyslipidemia in the era of COVID-19.
2020 年 3 月，COVID-19 疫情被宣布为大流行。许多 SARS-CoV-2 感染患者存在糖尿病、心血管疾病（CVD）和高血压等潜在慢性医疗条件。如果存在相关合并症，患者相关结局则更差。我们针对 COVID-19 感染期间糖尿病患者的最佳管理方法，尚无足够的证据。胰岛素抵抗和 CVD 共同增加了机体的炎症状态，这可能导致 COVID-19 严重程度增加，并在其中发挥一定作用。因此，除了控制血糖异常，还应针对其他 CVD 风险因素进行治疗。我们探讨了糖尿病与 COVID-19 之间可能存在的病理生理联系，并讨论了在 COVID-19 时代治疗血糖异常、高血压和血脂异常的各种选择。
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